还可以
Mab Aspartate Decarboxylase-IN-1 是天冬氨酸脱羧酶 (PanD)的有效抑制剂(IC50 = 56.3 μM)，具有抗菌活性。
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还可以Mab Aspartate Decarboxylase-IN-1 是天冬氨酸脱羧酶 (PanD)的有效抑制剂(IC50 = 56.3 μM)，具有抗菌活性。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 867 | 5日内发货 | |
| 5 mg | ¥ 1,490 | 5日内发货 | |
| 25 mg | ¥ 5,970 | 6-8周 | |
| 50 mg | ¥ 7,920 | 6-8周 | |
| 100 mg | ¥ 12,500 | 6-8周 |
| 产品描述 | Mab Aspartate Decarboxylase-IN-1 is a potent inhibitor of aspartate decarboxylase (PanD) (IC50 = 56.3 μM) with antibacterial activity [1]. |
| 体外活性 | Mab Aspartate Decarboxylase-IN-1 (compound analogue 2) shows inhibits against the mutants Mab PanDE119A, Mab PanDS135A and Mab PanDY126A mutants with the inhibition rates of 70.5%, 74.4%, 81.8%, respectively [1]. Mab Aspartate Decarboxylase-IN-1 (0-200 μM) shows inhibition on mycobacterium abscessus (Mab) PanD enzyme activity in the conversion of l-Asp to β-Ala with an IC 50 value of 56.3±4.8 μM [1]. Mab Aspartate Decarboxylase-IN-1 (0-4 mM) shows antibacterial activity for M. abscessus subsp. abscessus ATCC 19977 with an IC 50 value of 0.7mM, and M. abscessus subsp. bolletii CCUG 50184T, M. abscessus subsp. massiliense CCUG 48898T, M. abscessus subsp. abscessus Bamboo, M. abscessus subsp. abscessus ATCC 19977 with IC 50 s of 1-2 mM [1]. Mab Aspartate Decarboxylase-IN-1 shows mainly electrostatic- and hydrogen bonding interaction with the target enzyme [1]. |
| 分子量 | 293.28 |
| 分子式 | C16H11N3O3 |
| CAS No. | 2755712-12-8 |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 一共给药动物 10 只 ，您使用的配方为 5% 
DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH2O， 那么您的工作液浓度为 2 mg/mL 。 母液，添加 300 μLPEG300 混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH2O 混匀澄清 以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
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