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Anti-CD204/MSR1 Antibody (4Z10)
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产品编号 TMAY-03126
别名 macrophage scavenger receptor 1
Anti-CD204/MSR1 Antibody (4Z10) 是一种 Rabbit 抗体，靶向 CD204/MSR1。Anti-CD204/MSR1 Antibody (4Z10) 可用于 IHC-P,FCM,ICC/IF。
Anti-CD204/MSR1 Antibody (4Z10)
Anti-CD204/MSR1 Antibody (4Z10)
还可以产品编号 TMAY-03126 别名 macrophage scavenger receptor 1
Anti-CD204/MSR1 Antibody (4Z10) 是一种 Rabbit 抗体，靶向 CD204/MSR1。Anti-CD204/MSR1 Antibody (4Z10) 可用于 IHC-P,FCM,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 795 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD204/MSR1 Antibody (4Z10) is a Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Antibody (4Z10) can be used in IHC-P,FCM,ICC/IF. |
| 别名 | macrophage scavenger receptor 1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 4Z10 |
| 交叉反应 | Mouse |
| 验证活性 | 1. Confocal immunofluorescence analysis of Mouse MSR1 in RAW264.7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Mouse MSR1 monoclonal antibody (1:100) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to plasma membrane. 2. Immunochemical staining of mouse MSR1 in mouse liver with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 3. Flow cytometric analysis of Mouse MSR1(CD204) expression on Raw264.7 cells. Cells were stained with purified anti-Mouse MSR1(CD204), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | |
| 推荐剂量 | IHC-P: 1:50-1:200; ICC-IF: 1:50-1:1000; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MSR1 / CD204 (rM MSR1 / CD204; TMPY-00528; AAH03814.1; Trp 83-Val 354). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low-density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | FITC/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Protein: Mouse MSR1 / CD204 protein (TMPY-00528) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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