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顶部生物活性储存和溶解信息计算器

Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody

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Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody
产品编号 TMAC-01780
别名 p-HDAC4/5/9 (Ser246/259/220), p-HDAC4/5/9 (S246/259/220), HDAC4/5/9 (p-Ser246/259/220), HDAC4/5/9 (p-S246/259/220)

Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-HDAC4/5/9 (Ser246/259/220)。Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody

Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody
产品编号 TMAC-01780 别名 p-HDAC4/5/9 (Ser246/259/220), p-HDAC4/5/9 (S246/259/220), HDAC4/5/9 (p-Ser246/259/220), HDAC4/5/9 (p-S246/259/220)

Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-HDAC4/5/9 (Ser246/259/220)。Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,495
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100 μL
¥ 2,235
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产品介绍

生物活性
产品描述
Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HDAC4/5/9 (Ser246/259/220). Anti-Phospho-HDAC4/5/9 (Ser246/259/220) Polyclonal Antibody can be used in WB,IHC.
别名p-HDAC4/5/9 (Ser246/259/220), p-HDAC4/5/9 (S246/259/220), HDAC4/5/9 (p-Ser246/259/220), HDAC4/5/9 (p-S246/259/220)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extracts from 293 cells and Hela cells treated with serum using HDAC4/HDAC5/HDAC9 (phospho-Ser246/259/220) Antibody TMAC-01780.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HDAC4/HDAC5/HDAC9 (Phospho-Ser246/259/220) Antibody TMAC-01780 (left) or the same antibody preincubated with blocking peptide (right).
3. Western blot analysis of extracts from 293 cells untreated or treated with EGF using HDAC4/HDAC5/HDAC9 (phospho-Ser246/259/220) Antibody TMAC-01780.
应用
WB
IHC
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups from lysine residues in histones and non-histone proteins, resulting in transcriptional repression. In general,they do not act autonomously but as components of large multiprotein complexes, such as pRb-E2F and mSin3A, that mediate important transcription regulatory pathways. There are three classes of HDACs; classes 1, 2 and 4, which are closely related Zn2+-dependent enzymes. HDACs are ubiquitously expressed and they can exist in the nucleus or cytosol. Their subcellular localization is effected by protein-protein interactions (for example HDAC-14.3.3 complexes are retained in the cytosol) and by the class to which they belong (class 1 HDACs are predominantly nuclear whilst class 2 HDACs shuttle between the nucleus and cytosol). HDACs have a role in cell growth arrest, differentiation and death and this has led to substantial interest in HDAC inhibitors as possible antineoplastic agents.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 246/259/220 (T-A-S(p)-EP) derived from Human HDAC4/HDAC5/HDAC9
抗原种属
human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pHDAC4/5/9 (Ser246/259/220)pHDAC4/5/9 (S246/259/220)HDAC4/5/9 (pSer246/259/220)HDAC4/5/9 (pS246/259/220)HDAC4/5/9 (phospho-Ser246/259/220)HDAC4/5/9 (phospho-S246/259/220)

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