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别名 TMEM173, sting, Stimulator of interferon genes protein, Mediator of IRF3 activation
Anti-Sting Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Sting。Anti-Sting Polyclonal Antibody 可用于 WB。
Anti-Sting Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Sting。Anti-Sting Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
Anti-Sting Polyclonal Antibody 相关产品
| 产品描述 | Anti-Sting Polyclonal Antibody is a Rabbit antibody targeting Sting. Anti-Sting Polyclonal Antibody can be used in WB. |
| 别名 | TMEM173, sting, Stimulator of interferon genes protein, Mediator of IRF3 activation |
| Ig Type | IgG |
| 交叉反应 | Mouse,Rat (predicted:Human) |
| 验证活性 | Sample: Lane 1: Mouse Lung tissue lysates Lane 2: Mouse Uterus tissue lysates Lane 3: Mouse Thymus tissue lysates Lane 4: Mouse Large intestine tissue lysates Lane 5: Rat Lung tissue lysates Lane 6: Rat Uterus tissue lysates Lane 7: Rat Thymus tissue lysates Lane 8: Rat Large intestine tissue lysates Primary: Anti-STING1 (TMAB-01790) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kDa Observed band size: 38 kDa ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane. Mitochondrion outer membrane. Cell membrane. Cytoplasm > perinuclear region. In response to double-stranded DNA stimulation, relocalizes to perinuclear region, where the kinase TBK1 is recruited. |
| 组织特异性 | Ubiquitously expressed. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
| 免疫原 | KLH conjugated synthetic peptide: human STING1 |
| 抗原种属 | Human |
| 基因名称 | STING1 |
| 基因ID | |
| 蛋白名称 | Stimulator of interferon genes protein |
| Uniprot ID | |
| 研究领域 | NFkB pathway,NFkB pathway,Antiviral Signaling,Interferons,Transmembrane |
| 功能 | Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. |
| 分子量 | Theoretical: 42 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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