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Anti-Phospho-SMAD2 (Ser255) Antibody (1S198)
还可以产品编号 TMAH-00964
别名 SMAD2 (p-Ser255), SMAD2 (p-S255), p-SMAD2 (Ser255), p-SMAD2 (S255), Phospho-SMAD2 (S255)
Anti-Phospho-SMAD2 (Ser255) Antibody (1S198) 是一种抗体，靶向 Phospho-SMAD2 (Ser255)。Anti-Phospho-SMAD2 (Ser255) Antibody (1S198) 可用于 ELISA, IF。
Anti-Phospho-SMAD2 (Ser255) Antibody (1S198)
Anti-Phospho-SMAD2 (Ser255) Antibody (1S198)
还可以产品编号 TMAH-00964 别名 SMAD2 (p-Ser255), SMAD2 (p-S255), p-SMAD2 (Ser255), p-SMAD2 (S255), Phospho-SMAD2 (S255)
Anti-Phospho-SMAD2 (Ser255) Antibody (1S198) 是一种抗体，靶向 Phospho-SMAD2 (Ser255)。Anti-Phospho-SMAD2 (Ser255) Antibody (1S198) 可用于 ELISA, IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-SMAD2 (Ser255) Antibody (1S198) is an antibody targeting Phospho-SMAD2 (Ser255). Anti-Phospho-SMAD2 (Ser255) Antibody (1S198) can be used in ELISA, IF. |
| 别名 | SMAD2 (p-Ser255), SMAD2 (p-S255), p-SMAD2 (Ser255), p-SMAD2 (S255), Phospho-SMAD2 (S255) |
| Ig Type | Rabbit IgG |
| 克隆号 | 1S198 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of A549 cells with TMAH-00964 at 1:100,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L). |
| 应用 | ELISA, IF |
| 推荐剂量 | IF:1:20-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Phospho-SMAD2 (S255) |
| 抗原种属 | Human |
| 基因ID | 4087 |
| Uniprot ID | |
| 研究领域 | Signal Transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
关键词
SMAD2 (pSer255)SMAD2 (pS255)SMAD2 (phospho-Ser255)SMAD2 (phospho-S255)SMAD2SMAD family member 2 (SMAD 2;Smad2;hSMAD2)SMAD 2pSMAD2 (Ser255)pSMAD2 (S255)Mothers against DPP homolog 2Mothers against decapentaplegic homolog 2Mad-related protein 2 (hMAD-2)MADR2MADR 2MADH2MADH 2MAD homolog2MAD homolog 2JV18-1JV 18-1hMAD-2hMAD2
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