Anti-KDM1B Antibody (8C367) is a Rabbit antibody targeting KDM1B. Anti-KDM1B Antibody (8C367) can be used in WB,IP.

IgG

8C367

Human

25 μg total protein per lane of various lysates (see on figure) probed with KDM1B monoclonal antibody, unconjugated (TMAB-07975) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.

WB: 1:500-2000; IP: 1:20-50

Monoclonal

A synthesized peptide: human KDM1B

Human

KDM1B

Lysine-specific histone demethylase 1B

Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.