Anti-CD6 Antibody (9H618)

Name: Anti-CD6 Antibody (9H618)
Brand: TargetMol
SKU: TMAY-03424
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03424

Anti-CD6 Antibody (9H618) 是一种 Rabbit 抗体，靶向 CD6。Anti-CD6 Antibody (9H618) 可用于 FCM。

Anti-CD6 Antibody (9H618)

还可以

产品编号 TMAY-03424

Anti-CD6 Antibody (9H618) 是一种 Rabbit 抗体，靶向 CD6。Anti-CD6 Antibody (9H618) 可用于 FCM。

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生物活性

产品描述	Anti-CD6 Antibody (9H618) is a Rabbit antibody targeting CD6. Anti-CD6 Antibody (9H618) can be used in FCM.
Ig Type	Monoclonal Rabbit IgG
克隆号	9H618
交叉反应	Mouse
验证活性	Flow cytometric analysis of CD6 expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse CD6, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用	FCM
推荐剂量	FCM: 1:25-1:100
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD6 / Cluster of Differentiation 6 (rM CD6 / Cluster of Differentiation 6; TMPY-02254; Q91WN5; Met1-Gly396).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	T-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.

偶联与修饰

偶联	Unconjugated
其他可选修饰符	APC/PerCP/FITC/PE
可提供抗体种类	5

抗原信息

免疫原	Recombinant Mouse CD6 / Cluster of Differentiation 6 Protein (TMPY-02254)
抗原种属	Mouse
研究领域	ITIM/ITAM Immunoreceptors and Related Molecules

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.