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TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated

TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated

产品编号 TMPJ-00259
别名: G-TSF, 转化生长因子, Cetermin, Transforming growth factor beta-2 proprotein, Transforming growth factor β-2, TGF-β2, Glioblastoma-derived T-cell suppressor factor, TGFB2

TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P61812.

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TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
规格 价格/CNY 货期 数量
20 μg ¥ 5,730 5日内发货
100 μg ¥ 15,800 5日内发货
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产品目录号及名称: TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated (TMPJ-00259)
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生物活性
技术参数
产品性质
生物活性 Immobilized Human TGFBR2-Fc at 2μg/ml (100 μl/well)can bind Biotinylated Human TGF-beta 2-Avi . The ED50 of Biotinylated Human TGF-beta 2-Avi is 18.30 ng/ml. (Regularly tested)
产品描述 TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P61812.
种属 Human
表达系统 HEK293 Cells
标签 N-Avi
蛋白编号 P61812
别名 G-TSF, 转化生长因子, Cetermin, Transforming growth factor beta-2 proprotein, Transforming growth factor β-2, TGF-β2, Glioblastoma-derived T-cell suppressor factor, TGFB2
氨基酸序列 Ala303-­Ser414
蛋白构建 Ala303-­Ser414
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 10-14 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 4 mM HCl.
复溶方法 Reconstitute the lyophilized protein in 4mM HCl. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGFB2 could be a potential biomarker for screening, surveillance and prognosis in GC, and that TGFB2 might drive EMT in GC through the NGF/TrKs pathway. Overexpression of TGFB2 may drive EMT through the neuriterelated signaling and affect TMB levels by regulating the DNA damage repair pathways and immune infiltrates.TGF-β2 is an immune suppressor involvedin the development of immune tolerance, and recombinant TGF-β2 incubation is more potent than TGF-β1 or TGF-β3 incubation in suppressing macrophage inflammatory responses.

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Keywords

TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated G-TSF 转化生长因子 Cetermin TGFB-2 TGFB 2 Transforming growth factor b-2 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor β-2 TGF-β2 Glioblastoma-derived T-cell suppressor factor TGFB2 Transforming growth factor β-2 proprotein recombinant recombinant-proteins proteins protein

 

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