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Anti-Transglutaminase 2/TGM2 Antibody (3C930)
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产品编号 TMAY-01634
别名 transglutaminase 2, TGC, TG2, HEL-S-45, G-α-h, GNAH, G-ALPHA-h
Anti-Transglutaminase 2/TGM2 Antibody (3C930) 是一种 Rabbit 抗体，靶向 Transglutaminase 2/TGM2。Anti-Transglutaminase 2/TGM2 Antibody (3C930) 可用于 ELISA。
Anti-Transglutaminase 2/TGM2 Antibody (3C930)
Anti-Transglutaminase 2/TGM2 Antibody (3C930)
还可以产品编号 TMAY-01634 别名 transglutaminase 2, TGC, TG2, HEL-S-45, G-α-h, GNAH, G-ALPHA-h
Anti-Transglutaminase 2/TGM2 Antibody (3C930) 是一种 Rabbit 抗体，靶向 Transglutaminase 2/TGM2。Anti-Transglutaminase 2/TGM2 Antibody (3C930) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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偶联与修饰
抗原信息
| 产品描述 | Anti-Transglutaminase 2/TGM2 Antibody (3C930) is a Rabbit antibody targeting Transglutaminase 2/TGM2. Anti-Transglutaminase 2/TGM2 Antibody (3C930) can be used in ELISA. |
| 别名 | transglutaminase 2, TGC, TG2, HEL-S-45, G-α-h, GNAH, G-ALPHA-h |
| Ig Type | Rabbit IgG |
| 克隆号 | 3C930 |
| 交叉反应 | Human |
| 应用 | |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human TGM2 / Transglutaminase 2 (rh TGM2 / Transglutaminase 2; TMPY-01355; NP_004604.2; Met 1-Ala 687). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which catalyzes transamidation reactions or acts as a G-protein in intracellular signalling. As an enzyme which is responsible for the majority of transglutaminase (TG) activity in the brain, TGM2 is likely to play a modulatory role in nervous system development and has regulatory effect on neuronal cell death as well. Most importantly, numerous studies have presented data demonstrating that dysregulation of TGM2 may contribute to the pathogenesis of many neurodegenerative disorders, including Huntington's disease, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis as well as nervous system injuries. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human TGM2 / Transglutaminase 2 protein (TMPY-01355) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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