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Anti-ADRB2 Antibody (3B949)

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Anti-ADRB2 Antibody (3B949)
产品编号 TMAC-00420
别名 Beta-2 adrenoreceptor, Beta-2 adrenoceptor, Beta-2 adrenergic receptor, B2AR, ADRB2R, ADRB 2

Anti-ADRB2 Antibody (3B949) 是一种 Rabbit 抗体,靶向 ADRB2。Anti-ADRB2 Antibody (3B949) 可用于 WB,IHC,IP。

Anti-ADRB2 Antibody (3B949)

Anti-ADRB2 Antibody (3B949)

Rating icon 还可以
Anti-ADRB2 Antibody (3B949)
产品编号 TMAC-00420 别名 Beta-2 adrenoreceptor, Beta-2 adrenoceptor, Beta-2 adrenergic receptor, B2AR, ADRB2R, ADRB 2

Anti-ADRB2 Antibody (3B949) 是一种 Rabbit 抗体,靶向 ADRB2。Anti-ADRB2 Antibody (3B949) 可用于 WB,IHC,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADRB2 Antibody (3B949) is a Rabbit antibody targeting ADRB2. Anti-ADRB2 Antibody (3B949) can be used in WB,IHC,IP.
别名Beta-2 adrenoreceptor, Beta-2 adrenoceptor, Beta-2 adrenergic receptor, B2AR, ADRB2R, ADRB 2
Ig Type
IgG
交叉反应
Human,Mouse,Rat,zebrafish
验证活性
1. Western blot analysis of ADRB2 on zebrafish lysates using anti-ADRB2 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-ADRB2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-ADRB2 antibody. Counter stained with hematoxylin.
应用
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Adrenergic receptors (ARs) (the term "adrenergic" reflects the alternative name for epinephrine, adrenaline) include four general types (a1, a2, b1 and b2) which are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. cDNA clones have been isolated for all of the major AR subtypes and a number of closely related receptors have been identified by this approach. Each of the receptors have been shown to consist of single polypeptide chains which transverse the plasma membrane seven times, presumably forming a bundle of helices within the membrane. These transmembrane regions are hydrophobic and are interconnected by extracellular and intracellular hydrophilic loops. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins and is regulated by G protein-coupled receptor kinases (GRKs), cAMP-dependent protein kinase A and protein kinase C directed phosphorylation. b2-adrenergic receptors bind cathecholamines (epinephrine, norepinephrine) and influence development, behavior, cardiac function, smooth muscle tone, and metabolism. b2-AR signaling complexes can contain C L-type calcium channel Ca(V)1.2, G protein, adenylyl cyclase, cAMP-dependent kinase, and PP2A phosphatase.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 60 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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