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Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AurB/C (Thr236/202)。Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody 可用于 IHC。
Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AurB/C (Thr236/202)。Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody 可用于 IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AurB/C (Thr236/202). Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody can be used in IHC. |
别名 | p-AurB/C (Thr236/202), p-AurB/C (T236/202), AurB/C (p-Thr236/202), AurB/C (p-T236/202) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Immunohistochemistry analysis of paraffin-embedded human brain tissue using AurB/C (Phospho-Thr236/202) antibody TMAC-00348. The picture on the right is treated with the synthesized peptide. |
应用 | |
推荐剂量 | IHC: 1:50-100 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of threonine 236/202 (C-G-T(p)-L-D) derived from Human AurB/C |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 35 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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