Name: Vopratelimab
Brand: TargetMol
SKU: T77434
Price: 3290 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 3,290

现货

5 mg

¥ 7,260

现货

10 mg

¥ 9,790

现货

25 mg

¥ 14,500

现货

50 mg

¥ 19,600

现货

生物活性

产品描述	Vopratelimab (JTX-2011) is a selective humanized immunoglobulin G1-kappa monoclonal antibody that is a potent ICOS agonist. Vopratelimab has a high affinity for inducible T cell CO stimulating factors (ICOS), with an affinity of 0.93 nM for hICOS, 3.7 nM for rat ICOS, and 0.64 nM for mICOS. Vopratelimab has an anti-tumor immune effect and can be used to improve metastatic non-small cell lung cancer.
体外活性	Vopratelimab（JTX-2011；0.001-10 μg/mL；3天；CD4 T细胞）展现了激活初级人类T细胞的活性，促进分泌IFNγ、IL-17a、IL-10、IL-9、GM-CSF、TNFα和IL-21[1]。
体内活性	Vopratelimab（JTX-2011；0.25-0.3 mg/kg；i.p.；每周两次，连续两周）在Sa1/N 同源小鼠肿瘤模型中促进肿瘤退化[1]。
别名	伏派利单抗, JTX 2011
反应种属	Human
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
内毒素	< 1 EU/mg as determined by the LAL method

抗体信息

同型	Human IgG1 kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

分子量	145.74 kDa
CAS No.	2039148-04-2

储存&溶解度

存储	store at low temperature \| -20°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.

Vopratelimab