规格

价格

库存

数量

25 mg

¥ 6,320

8-10周

50 mg

¥ 8,210

8-10周

100 mg

¥ 13,200

8-10周

生物活性

产品描述	EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.
体内活性	EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function.EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversal rate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups.
别名	F1013

化学信息

分子量	382.38
分子式	C₁₈H₂₃FN₂O₆
CAS No.	223568-55-6
Smiles	[C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)[C@H](C)C)=O)(C(CF)=O)CC(O)=O
密度	1.258 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 60 mg/mL (156.91 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2.5 mg/mL (6.54 mM), Sonication is recommeded.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO