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Anti-TIMP-1 Antibody (9G112)

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Anti-TIMP-1 Antibody (9G112)
产品编号 TMAY-03242
别名 TIMP metallopeptidase inhibitor 1

Anti-TIMP-1 Antibody (9G112) 是一种 Rabbit 抗体,靶向 TIMP-1。Anti-TIMP-1 Antibody (9G112) 可用于 ELISA。

Anti-TIMP-1 Antibody (9G112)
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Anti-TIMP-1 Antibody (9G112)

Rating icon 还可以
Anti-TIMP-1 Antibody (9G112)
产品编号 TMAY-03242 别名 TIMP metallopeptidase inhibitor 1

Anti-TIMP-1 Antibody (9G112) 是一种 Rabbit 抗体,靶向 TIMP-1。Anti-TIMP-1 Antibody (9G112) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-TIMP-1 Antibody (9G112) is a Rabbit antibody targeting TIMP-1. Anti-TIMP-1 Antibody (9G112) can be used in ELISA.
别名TIMP metallopeptidase inhibitor 1
Ig Type
Rabbit IgG
克隆号
9G112
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TIMP-1 (rM TIMP-1; TMPY-01485; NP_035723.2; Met1-Arg205).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse TIMP-1 Protein (TMPY-01485)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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