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顶部生物活性储存和溶解信息计算器

Anti-PLAU/uPA Antibody (8V289)

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Anti-PLAU/uPA Antibody (8V289)
产品编号 TMAC-04199
别名 Urokinase, URK, u-PA, UPA, QPD, PLAU, BDPLT5, ATF

Anti-PLAU/uPA Antibody (8V289) 是一种 Rabbit 抗体，靶向 PLAU/uPA。Anti-PLAU/uPA Antibody (8V289) 可用于 WB,IHC。

Anti-PLAU/uPA Antibody (8V289)

Anti-PLAU/uPA Antibody (8V289)

Rating icon 还可以
Anti-PLAU/uPA Antibody (8V289)
产品编号 TMAC-04199 别名 Urokinase, URK, u-PA, UPA, QPD, PLAU, BDPLT5, ATF

Anti-PLAU/uPA Antibody (8V289) 是一种 Rabbit 抗体，靶向 PLAU/uPA。Anti-PLAU/uPA Antibody (8V289) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-PLAU/uPA Antibody (8V289) is a Rabbit antibody targeting PLAU/uPA. Anti-PLAU/uPA Antibody (8V289) can be used in WB,IHC.
别名Urokinase, URK, u-PA, UPA, QPD, PLAU, BDPLT5, ATF
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Urokinase on MCF-7 cells lysates using anti-Urokinase antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human liver carcinoma tissue using anti-Urokinase antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using anti-Urokinase antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Urokinase antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Urokinase antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Urokinase plasminogen activator receptor (uPAR), also designated CD87, is a glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum b-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a Trypsin- like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. This pathway is observed during re-epithelialization of lesions, wound healing and tissue remodeling. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial origin tumor cells and are required for tumor invasion and metastasis. Ras, MEK, ERK and MLCK function as downstream effectors in the uPAR-dependent signaling cascade, which is initiated by uPA binding, and promotes cellular migration in an integrin selective manner.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P00749
化学信息
分子量Theoretical: 49 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

BDPLT-5BDPLT 5

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