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Anti-GPVI Polyclonal Antibody
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产品编号 TMAB-00804
别名 MGC138168, GPVI, Gp6, Glycoprotein 6
Anti-GPVI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPVI。Anti-GPVI Polyclonal Antibody 可用于 WB。
Anti-GPVI Polyclonal Antibody
Anti-GPVI Polyclonal Antibody
还可以产品编号 TMAB-00804 别名 MGC138168, GPVI, Gp6, Glycoprotein 6
Anti-GPVI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPVI。Anti-GPVI Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-GPVI Polyclonal Antibody is a Rabbit antibody targeting GPVI. Anti-GPVI Polyclonal Antibody can be used in WB. |
| 疾病造模方案 | |
| 别名 | MGC138168, GPVI, Gp6, Glycoprotein 6 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat (predicted:Pig,Cow,Horse) |
| 验证活性 | Sample: Lane 1: Mouse Spleen Lysates Lane 2: Mouse Testis Lysates Lane 3: Rat Spleen Lysates Lane 4: Rat Testis Lysates Lane 5: Human K562 cell Lysates Lane 6: Human U-2 OS cell Lysates Primary: Anti-Glycoprotein VI (TMAB-00804) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 35 kDa Observed band size: 65 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform 1: Cell membrane; Single-pass membrane protein. Isoform 2: Cell membrane; Single-pass membrane protein. |
| 组织特异性 | Megakaryocytes and platelets. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. |
| 免疫原 | KLH conjugated synthetic peptide: human GPVI/Glycoprotein VI |
| 抗原种属 | Human |
| 基因名称 | GP6 |
| 基因ID | |
| 蛋白名称 | Platelet glycoprotein VI |
| Uniprot ID | |
| 功能 | Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2. |
| 分子量 | Theoretical: 35 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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