首页 工具
登录
购物车

搜索结果

Search Results for " inhibitor "
Targets Recommended: Carboxypeptidase

10000

抑制剂 & 化合物

1000+

天然产物

17

化合物库

94

TargetMol 试剂盒

434

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name
L2000 抑制剂库

8418 compounds
8418 个小分子抑制剂的独特集合,主要用于细胞信号研究、新药筛选、高通量筛选和高内涵筛选;
L9100 磷酸酶抑制剂化合物库

80 compounds
80 种已知活性的磷酸酶抑制剂的集合,可用于化合物筛选、化学基因组学、药理分析等方面;
L1600 激酶抑制剂库

2230 compounds
2230 种激酶抑制剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选;
L7600 趋化因子抑制剂库

59 compounds
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选;
L9400 PPI抑制剂库

490 compounds
490 种已知活性的 PPI 相关的抑制剂,可用于高通量、高内涵筛选;
L1400 MAPK 抑制剂库

367 compounds
367 种与MAPK 信号通路相关的生物活性小分子化合物的特有集合,可用于高通量筛选和高内涵筛选;
L1100 蛋白酶抑制剂库

344 compounds
344 种已知的小分子蛋白酶抑制剂的特有集合,可用于高通量筛选和高内涵筛选;
L9410 共价抑制剂库

1949 compounds
1949 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发;
L3600 细胞因子抑制剂库

613 compounds
613 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体;
L2200 酪氨酸激酶分子库

1033 compounds
1033 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选;
L2300 离子通道库

946 compounds
946 种与离子通道相关的生物活性小分子化合物的特有集合,用于离子通道相关的疾病和药物研究,可用于高通量筛选和高内涵筛选;
L1610 FDA 上市激酶抑制剂库

280 compounds
TargetMol FDA 上市激酶库包含280 个具有明确激酶抑制活性的上市药物
L2010 高选择性抑制剂库

580 compounds
xunm种具有高选择性的抑制剂集合
L1510 核受体化合物库

546 compounds
546 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选;
L8000 干细胞分化化合物库

1213 compounds
1213 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选;
L7000 活性脂质化合物库

385 compounds
385 种生物活性小分子化合物,用于高通量、高内涵筛选;
L7110 抗高血压化合物库

719 compounds
719 种高血压相关的小分子,用于高通量和高内涵筛选;

化合物库

抑制剂库
Cat.No: L2000
Compounds: 8418
磷酸酶抑制剂化合物库
Cat.No: L9100
Compounds: 80
激酶抑制剂库
Cat.No: L1600
Compounds: 2230
趋化因子抑制剂库
Cat.No: L7600
Compounds: 59
PPI抑制剂库
Cat.No: L9400
Compounds: 490
MAPK 抑制剂库
Cat.No: L1400
Compounds: 367
蛋白酶抑制剂库
Cat.No: L1100
Compounds: 344
共价抑制剂库
Cat.No: L9410
Compounds: 1949
细胞因子抑制剂库
Cat.No: L3600
Compounds: 613
酪氨酸激酶分子库
Cat.No: L2200
Compounds: 1033
离子通道库
Cat.No: L2300
Compounds: 946
FDA 上市激酶抑制剂库
Cat.No: L1610
Compounds: 280
高选择性抑制剂库
Cat.No: L2010
Compounds: 580
核受体化合物库
Cat.No: L1510
Compounds: 546
干细胞分化化合物库
Cat.No: L8000
Compounds: 1213
活性脂质化合物库
Cat.No: L7000
Compounds: 385
抗高血压化合物库
Cat.No: L7110
Compounds: 719
Cat. No. Product Name Form Specificity Of Inhibition
C0002 Phosphatase Inhibitor Cocktail I (100× ddH2O)

磷酸酶抑制剂 Cocktail I

Solution (100× in ddH2O) Acid Phosphatase, Alkaline phosphatase, PTPs, ATPases
C0003 Phosphatase Inhibitor Cocktail II (100× DMSO)

磷酸酶抑制剂 Cocktail II

Solution (100× in DMSO) Alkaline phosphatases, Ser/Thr phosphatases, Acid and PP1 and PP2A
C0004 Phosphatase Inhibitor Cocktail III (2 Tubes, 100x)

磷酸酶抑制剂 Cocktail III

2 Tube Solution (100×) Each Tube has different specificity of inhibition
C0001 Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)

蛋白酶抑制剂 Cocktail

Solution (EDTA-Free,100× in DMSO) Serine proteases, Aminopeptidases, Cysteine proteases, Aspartic proteases
CL0064 PDE inhibitor kit

PDE inhibitor kit

CL0140 BTK inhibitor kit

BTK inhibitor kit

CL0128 HMGCR inhibitor kit

HMGCR inhibitor kit

CL0131 SGLT inhibitor kit

SGLT inhibitor kit

C0048 Deacetylase Inhibitor Cocktail (100× in 70% DMSO)

去乙酰化酶抑制剂 Cocktail(100× in 70% DMSO)

Solution (100× in 70% DMSO) Class I/II/III HDAC
CL0142 MMP inhibitor kit

MMP inhibitor kit

CL0121 ALK inhibitor kit

ALK inhibitor kit

CL0045 COX inhibitor kit

COX inhibitor kit

CL0056 CDK inhibitor kit

CDK inhibitor kit

CL0116 MAO inhibitor kit

MAO inhibitor kit

CL0114 ERK inhibitor kit

ERK inhibitor kit

CL0109 Ras inhibitor kit

Ras inhibitor kit

CL0084 FGFR inhibitor kit

FGFR inhibitor kit

CL0139 ROS inhibitor kit

ROS inhibitor kit

CL0069 JAK inhibitor kit

JAK inhibitor kit

CL0091 MEK inhibitor kit

MEK inhibitor kit

CL0071 PDGFR inhibitor kit

PDGFR inhibitor kit

CL0130 DUB inhibitor kit

DUB inhibitor kit

CL0052 HDAC inhibitor kit

HDAC inhibitor kit

CL0062 Topoisomerase inhibitor kit

Topoisomerase inhibitor kit

CL0081 Phosphatase inhibitor kit

Phosphatase inhibitor kit

CL0100 Raf inhibitor kit

Raf inhibitor kit

CL0072 BET inhibitor kit

BET inhibitor kit

CL0127 NOS inhibitor kit

NOS inhibitor kit

CL0085 HSP inhibitor kit

HSP inhibitor kit

CL0132 DHFR inhibitor kit

DHFR inhibitor kit

CL0133 CXCR inhibitor kit

CXCR inhibitor kit

CL0087 mTOR inhibitor kit

mTOR inhibitor kit

CL0083 Dehydrogenase inhibitor kit

Dehydrogenase inhibitor kit

CL0101 STAT inhibitor kit

STAT inhibitor kit

CL0125 AChE inhibitor kit

AChE inhibitor kit

CL0146 JNK inhibitor kit

JNK inhibitor kit

CL0068 VEGFR inhibitor kit

VEGFR inhibitor kit

CL0058 EGFR inhibitor kit

EGFR inhibitor kit

CL0112 PKC inhibitor kit

PKC inhibitor kit

CL0122 ACE inhibitor kit

ACE inhibitor kit

CL0093 PARP inhibitor kit

PARP inhibitor kit

CL0135 ROCK inhibitor kit

ROCK inhibitor kit

CL0098 HER2 inhibitor kit

HER2 inhibitor kit

CL0077 Reverse Transcriptase inhibitor kit

Reverse Transcriptase inhibitor kit

CL0102 Akt inhibitor/activator kit

Akt inhibitor/activator kit

CL0129 Aurora Kinase inhibitor kit

Aurora Kinase inhibitor kit

CL0076 PPAR inhibitor/activator kit

PPAR inhibitor/activator kit

CL0138 Carbonic Anhydrase inhibitor kit

Carbonic Anhydrase inhibitor kit

CL0094 FLT3 inhibitor kit

FLT3 inhibitor kit

CL0066 P450 inhibitor kit

P450 inhibitor kit

CL0118 p38 inhibitor kit

p38 inhibitor kit

CL0117 DPP4 inhibitor kit

DPP4 inhibitor kit

CL0092 GSK-3 inhibitor kit

GSK-3 inhibitor kit

CL0075 c-Kit inhibitor kit

c-Kit inhibitor kit

CL0115 Proton Pump inhibitor kit

Proton Pump inhibitor kit

CL0107 Src inhibitor/activator kit

Src inhibitor/activator kit

CL0082 TRP Channel inhibitor kit

TRP Channel inhibitor kit

CL0074 Microtubule/Tubulin inhibitor kit

Microtubule/Tubulin inhibitor kit

CL0059 Dopamine Receptor inhibitor kit

Dopamine Receptor inhibitor kit

CL0063 Cytoskeleton pathway inhibitor kit

Cytoskeleton pathway inhibitor kit

CL0105 Sirtuin inhibitor/activator kit

Sirtuin inhibitor/activator kit

CL0057 PI3K inhibitor kit

PI3K inhibitor kit

CL0145 Casein Kinase inhibitor kit

Casein Kinase inhibitor kit

CL0055 Potassium Channel inhibitor kit

Potassium Channel inhibitor kit

CL0136 ATM/ATR inhibitor kit

ATM/ATR inhibitor kit

CL0088 Angiotensin Receptor inhibitor kit

Angiotensin Receptor inhibitor kit

CL0067 Sodium Channel inhibitor kit

Sodium Channel inhibitor kit

CL0119 Histone Demethylase inhibitor kit

Histone Demethylase inhibitor kit

CL0079 Adenosine Receptor inhibitor kit

Adenosine Receptor inhibitor kit

CL0070 GABA Receptor inhibitor kit

GABA Receptor inhibitor kit

CL0060 Estrogen Receptor inhibitor kit

Estrogen Receptor inhibitor kit

CL0061 Histone Methyltransferase inhibitor kit

Histone Methyltransferase inhibitor kit

CL0123 AMPK inhibitor/activator kit

AMPK inhibitor/activator kit

CL0141 Notch pathway inhibitor kit

Notch pathway inhibitor kit

CL0149 β-/γ-secretase inhibitor kit

β-/γ-secretase inhibitor kit

CL0147 c-FMS inhibitor kit

c-FMS inhibitor kit

CL0134 p53 inhibitor/reactivator kit

p53 inhibitor/reactivator kit

CL0150 DNA Methyltransferase/Demethylase inhibitor kit

DNA Methyltransferase/Demethylase inhibitor kit

CL0090 RNA Synthesis inhibitor/activator kit

RNA Synthesis inhibitor/activator kit

CL0073 DNA synthesis inhibitor/activator kit

DNA synthesis inhibitor/activator kit

CL0143 PKA/cAMP inhibitor/activator kit

PKA/cAMP inhibitor/activator kit

CL0078 Glucocorticoid Receptor inhibitor/activator kit

Glucocorticoid Receptor inhibitor/activator kit

CL0089 c-Met/HGFR inhibitor kit

c-Met/HGFR inhibitor kit

CL0080 TGFβ signaling pathway inhibitor/activator kit

TGFβ signaling pathway inhibitor/activator kit

CL0053 NF-κB pathway inhibitor kit

NF-κB pathway inhibitor kit

CL0120 Bcr-Abl inhibitor/degrader kit

Bcr-Abl inhibitor/degrader kit

CL0113 ER stress pathway inhibitor/inducer kit

ER stress pathway inhibitor/inducer kit

CL0095 Hedgehog signaling pathway inhibitor/activator kit

Hedgehog signaling pathway inhibitor/activator kit

CL0106 HIF/HIF-PH inhibitor/activator kit

HIF/HIF-PH inhibitor/activator kit

CL0096 Wnt/β-catenin/PORCN inhibitor/activator kit

Wnt/β-catenin/PORCN inhibitor/activator kit

CL0137 E1/E2/E3 Enzyme inhibitor kit

E1/E2/E3 Enzyme inhibitor kit

C0047 RIPA Lysis Buffer (Weak)

RIPA裂解液(弱)

Solution in bottle
C0046 RIPA Lysis Buffer (Middle)

RIPA裂解液(中)

Solution in bottle
C0045 RIPA Lysis Buffer (Strong)

RIPA裂解液(强)

Solution in bottle

TargetMol 试剂盒

磷酸酶抑制剂 Cocktail I
Cat.No: C0002
磷酸酶抑制剂 Cocktail II
Cat.No: C0003
磷酸酶抑制剂 Cocktail III
Cat.No: C0004
蛋白酶抑制剂 Cocktail
Cat.No: C0001
PDE inhibitor kit
Cat.No: CL0064
BTK inhibitor kit
Cat.No: CL0140
HMGCR inhibitor kit
Cat.No: CL0128
SGLT inhibitor kit
Cat.No: CL0131
去乙酰化酶抑制剂 Cocktail(100× in 70% DMSO)
Cat.No: C0048
MMP inhibitor kit
Cat.No: CL0142
ALK inhibitor kit
Cat.No: CL0121
COX inhibitor kit
Cat.No: CL0045
CDK inhibitor kit
Cat.No: CL0056
MAO inhibitor kit
Cat.No: CL0116
ERK inhibitor kit
Cat.No: CL0114
Ras inhibitor kit
Cat.No: CL0109
FGFR inhibitor kit
Cat.No: CL0084
ROS inhibitor kit
Cat.No: CL0139
JAK inhibitor kit
Cat.No: CL0069
MEK inhibitor kit
Cat.No: CL0091
PDGFR inhibitor kit
Cat.No: CL0071
DUB inhibitor kit
Cat.No: CL0130
HDAC inhibitor kit
Cat.No: CL0052
Topoisomerase inhibitor kit
Cat.No: CL0062
Phosphatase inhibitor kit
Cat.No: CL0081
Raf inhibitor kit
Cat.No: CL0100
BET inhibitor kit
Cat.No: CL0072
NOS inhibitor kit
Cat.No: CL0127
HSP inhibitor kit
Cat.No: CL0085
DHFR inhibitor kit
Cat.No: CL0132
CXCR inhibitor kit
Cat.No: CL0133
mTOR inhibitor kit
Cat.No: CL0087
Dehydrogenase inhibitor kit
Cat.No: CL0083
STAT inhibitor kit
Cat.No: CL0101
AChE inhibitor kit
Cat.No: CL0125
JNK inhibitor kit
Cat.No: CL0146
VEGFR inhibitor kit
Cat.No: CL0068
EGFR inhibitor kit
Cat.No: CL0058
PKC inhibitor kit
Cat.No: CL0112
ACE inhibitor kit
Cat.No: CL0122
PARP inhibitor kit
Cat.No: CL0093
ROCK inhibitor kit
Cat.No: CL0135
HER2 inhibitor kit
Cat.No: CL0098
Reverse Transcriptase inhibitor kit
Cat.No: CL0077
Akt inhibitor/activator kit
Cat.No: CL0102
Aurora Kinase inhibitor kit
Cat.No: CL0129
PPAR inhibitor/activator kit
Cat.No: CL0076
Carbonic Anhydrase inhibitor kit
Cat.No: CL0138
FLT3 inhibitor kit
Cat.No: CL0094
P450 inhibitor kit
Cat.No: CL0066
p38 inhibitor kit
Cat.No: CL0118
DPP4 inhibitor kit
Cat.No: CL0117
GSK-3 inhibitor kit
Cat.No: CL0092
c-Kit inhibitor kit
Cat.No: CL0075
Proton Pump inhibitor kit
Cat.No: CL0115
Src inhibitor/activator kit
Cat.No: CL0107
TRP Channel inhibitor kit
Cat.No: CL0082
Microtubule/Tubulin inhibitor kit
Cat.No: CL0074
Dopamine Receptor inhibitor kit
Cat.No: CL0059
Cytoskeleton pathway inhibitor kit
Cat.No: CL0063
Sirtuin inhibitor/activator kit
Cat.No: CL0105
PI3K inhibitor kit
Cat.No: CL0057
Casein Kinase inhibitor kit
Cat.No: CL0145
Potassium Channel inhibitor kit
Cat.No: CL0055
ATM/ATR inhibitor kit
Cat.No: CL0136
Angiotensin Receptor inhibitor kit
Cat.No: CL0088
Sodium Channel inhibitor kit
Cat.No: CL0067
Histone Demethylase inhibitor kit
Cat.No: CL0119
Adenosine Receptor inhibitor kit
Cat.No: CL0079
GABA Receptor inhibitor kit
Cat.No: CL0070
Estrogen Receptor inhibitor kit
Cat.No: CL0060
Histone Methyltransferase inhibitor kit
Cat.No: CL0061
AMPK inhibitor/activator kit
Cat.No: CL0123
Notch pathway inhibitor kit
Cat.No: CL0141
β-/γ-secretase inhibitor kit
Cat.No: CL0149
c-FMS inhibitor kit
Cat.No: CL0147
p53 inhibitor/reactivator kit
Cat.No: CL0134
DNA Methyltransferase/Demethylase inhibitor kit
Cat.No: CL0150
RNA Synthesis inhibitor/activator kit
Cat.No: CL0090
DNA synthesis inhibitor/activator kit
Cat.No: CL0073
PKA/cAMP inhibitor/activator kit
Cat.No: CL0143
Glucocorticoid Receptor inhibitor/activator kit
Cat.No: CL0078
c-Met/HGFR inhibitor kit
Cat.No: CL0089
TGFβ signaling pathway inhibitor/activator kit
Cat.No: CL0080
NF-κB pathway inhibitor kit
Cat.No: CL0053
Bcr-Abl inhibitor/degrader kit
Cat.No: CL0120
ER stress pathway inhibitor/inducer kit
Cat.No: CL0113
Hedgehog signaling pathway inhibitor/activator kit
Cat.No: CL0095
HIF/HIF-PH inhibitor/activator kit
Cat.No: CL0106
Wnt/β-catenin/PORCN inhibitor/activator kit
Cat.No: CL0096
E1/E2/E3 Enzyme inhibitor kit
Cat.No: CL0137
RIPA裂解液(弱)
Cat.No: C0047
RIPA裂解液(中)
Cat.No: C0046
RIPA裂解液(强)
Cat.No: C0045
Cat. No. Product Name Target Signaling Pathways
T10876 CPA inhibitor

Carboxypeptidase inhibitor

Carboxypeptidase Proteases/Proteasome
CPA inhibitor (Carboxypeptidase inhibitor) 是一种有效的羧肽酶 A (CPA) 抑制剂,Ki 值为 0.32 μM。
T5451 Eph inhibitor 2

Ehp-inhibitor-1

Ephrin Receptor Tyrosine Kinase/Adaptors
Eph inhibitor 2 是一种 Eph 家族酪氨酸激酶抑制剂。
T1804 HPGDS inhibitor 1

HPGDS-inhibitor-1

PGE Synthase Immunology/Inflammation
HPGDS inhibitor 1 是口服具有活性的HPGDS 选择性抑制剂,在酶和细胞分析中的IC50值分别为 0.6 nM 和 32 nM,但对 L-PGDS、mPGES、COX-1、COX-2 、5-LOX 无抑制作用。
T4338 USP7/USP47 inhibitor

USP7/47 inhibitor-1

DUB Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
USP7/USP47 inhibitor (USP7/47 inhibitor-1) 是一种选择性泛素特异性蛋白酶 7/47 抑制剂,EC50值分别为 0.42 μM 和 1.0 μM。
T5524 Aurora kinase inhibitor-3

Aurora Kinase Inhibitor III

Aurora Kinase Cell Cycle/Checkpoint; Chromatin/Epigenetic
Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) 是一种有效的,选择性 Aurora A 激酶抑制剂,IC50为 42 nM。
T2350 MALT1 inhibitor MI-2

MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor)

MALT Immunology/Inflammation
MI 2 (MALT1 inhibitor) 是一种MALT1抑制剂 (IC50=5.84 μM),对动物无毒性。它能够直接与 MALT1 结合,不可逆地抑制蛋白酶功能,并伴有 NF-κB 报告子活性抑制、c-REL 核定位抑制和 NF-κB 靶基因下调。
T8766 GOT1 inhibitor-1

GOT1 inhibitor 2c

Others Others
GOT1 inhibitor-1 (GOT1 inhibitor 2c) 是一种新型的、非共价的谷氨酸草酰乙酸转氨酶 1 (GOT1) 抑制剂(IC50:8.2 uM),是一种戊酸衍生物。 它可用于以及胰腺导管腺癌 (PDAC) 。
T5817 PKC-theta inhibitor hcl

PKC-theta inhibitor

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
PKC-theta inhibitor hcl 是一种选择性 PKC-θ 抑制剂 (IC50:12 nM)。
T3189 B7/CD28 interaction inhibitor 1

CTLA-4 inhibitor

Others Others
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) 是B7.1-CD28相互作用抑制剂(IC50:50 nM)。
T2074 Raf inhibitor 1

B-Raf inhibitor 1

Raf MAPK
Raf inhibitor 1 (B-Raf inhibitor 1)是Raf 激酶抑制剂,对B-RafWT、B-RafV600E 和 C-Raf 的Ki 分别为 1、1 和 0.3 nM。
T38683 SCD1 inhibitor-3

SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a

Dehydrogenase Metabolism
SCD1 inhibitor-3 (ML-270) 是一种高效、口服的化合物,可以抑制SCD1,且安全性极高。 SCD1 inhibitor-3 显示出在代谢疾病(包括肥胖、二型糖尿病和血脂异常,以及痤疮和癌症等各种皮肤病)方面的巨大研究潜力。
T3593 Src Inhibitor 1

Src Kinase Inhibitor 1,Src-l1

Src Angiogenesis; Tyrosine Kinase/Adaptors
Src Inhibitor 1 (Src Kinase Inhibitor 1) 是一种选择性的、高效的、ATP-竞争性的双位点 Src 酪氨酸激酶抑制剂,能够抑制 Src (IC50:44 nM) 和 Lck (IC50:88 nM)。
T3042 JAK2 Inhibitor V

JAK2 Inhibitor V Z3,Z3

JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
JAK2 Inhibitor V (JAK2 Inhibitor V Z3) 是一种新型的 Jak2 特异性抑制剂,以剂量依赖性方式抑制 Jak2-V617F 和 Jak2-WT 自磷酸化。
T6335 Tie2 kinase inhibitor 1

Tie2 kinase inhibitor

Tie-2 Tyrosine Kinase/Adaptors
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor) 是Tie2激酶选择性抑制剂9IC50:250 nM),具有抗癌作用。
T4191 Multi-kinase inhibitor 1

Multi-kinase inhibitor I

Others; Bcr-Abl; PDGFR; c-Kit Angiogenesis; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) 是多激酶抑制剂。它有用于导致与酪氨酸激酶活性异常或失控有关的疾病或失调的潜力,特别是与c-Kit,PDGF-R,Bcr-abl 活性相关的疾病。
T4391 Syk Inhibitor II dihydrochloride

Syk Inhibitor II (hydrochloride)

Others; Tyrosine Kinases; Syk; PKC; BTK Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors
Syk Inhibitor II (hydrochloride) 是一种非受体酪氨酸激酶,磷酸化后,它与 FcRγ 链的基于免疫受体酪氨酸的激活基序结合,并介导与血小板功能和炎症相关的下游信号传导。 Syk inhibitor II 是一种可渗透细胞的嘧啶-甲酰胺化合物,以 ATP 竞争性方式选择性和可逆地阻断 Syk (IC50 = 41 nM)。它对 PKCε、PKCβII、ZAP-70、Btk 和 Itk 的效力要低得多(IC50s 分别为5.1、11、11.2、15.5 和 22.6 μM)。
T10678 Carboxypeptidase G2 (CPG2) Inhibitor

CPG2 Inhibitor,Carboxypeptidase G2 Inhibitor

Carboxypeptidase Proteases/Proteasome
Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) 是新型的羧肽酶 G2(CPG2)抑制剂,显示出抗癌活性。
T2457 IRAK-1-4 Inhibitor I

IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor

IRAK Immunology/Inflammation; NF-κB
IRAK-1-4 Inhibitor I 是一种IRAK1/4双重抑制剂,其IC50分别为 0.2 μM 和 0.3 μM。
T67767 HIF-1 inhibitor-4

HIF-1 inhibitor-4

HIF Angiogenesis; Chromatin/Epigenetic
HIF-1 inhibitor-4 (HIF-1 inhibitor-4) 是一种 HIF-1 抑制剂 (IC50: 560 nM)。HIF-1 inhibitor-4 减少 HIF-1α 蛋白水平,但不影响 mRNA 水平。
T24141 HIV-1 Inhibitor 18A

HIV-1 Inhibitor-18A

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) 特异性抑制多种 HIV-1 分离株的进入。
T4167 Raf inhibitor 1 dihydrochloride

B-Raf inhibitor 1 dihydrochloride

Raf MAPK
Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) 是 Raf 激酶抑制剂,对 B-RafWT、B-RafV600E 和 C-Raf 的Ki 分别为 1、1 和 0.3 nM。
T35827L PKCε Inhibitor Peptide acetate

PKCε Inhibitor Peptide acetate(182683-50-7 Free base)

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
PKCε Inhibitor Peptide acetate 是一种特异性 PKCε 抑制剂,含有其特定受体活化 C 激酶 (RACK) 的位点。 PKCε Inhibitor Peptide acetate 抑制 PKCε 的转运,但不抑制 αPKC,βPKC 和 δPKC 的转运。
T4491 LMPTP INHIBITOR 1 hydrochloride

LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))

Phosphatase Metabolism
LMPTP INHIBITOR 1 hydrochloride 是一种高选择性的低分子量蛋白酪氨酸磷酸酶 (LMPTP) 抑制剂。LMPTP INHIBITOR 1 (hydrochloride) 能够抑制 LMPTP-A 的活性,IC50值为 0.8 μM。
T9040 Aurora kinase inhibitor-2

IUN-70219,Aurora Kinase Inhibitor II

Aurora Kinase Cell Cycle/Checkpoint; Chromatin/Epigenetic
Aurora kinase inhibitor-2 (IUN-70219) 是一种可渗透细胞的苯胺喹唑啉,可抑制极光激酶的活性,对Aurora A 和Aurora B 的IC50分别为 390 nM 和 240 nM。
T21954 EGFR/ErbB-2/ErbB-4 inhibitor-2

EGFR/ErbB2 Inhibitor

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) 是EGFR 和ErbB 的抑制剂,对EGFR、ErbB2 和 ErbB4 的IC50分别为 0.017、0.08 和 1.91 μM。
TP2008L Lyn peptide inhibitor acetate

Lyn peptide inhibitor acetate(222018-18-0 free base)

IL Receptor Immunology/Inflammation
Lyn peptide inhibitor acetate(222018-18-0 free base) 是一种有效的细胞渗透性 Lyn 偶联 IL-5 受体信号通路抑制剂,同时保持其他信号完整。它阻断 Lyn 活化并抑制 Lyn 酪氨酸激酶与 IL-3/GM-CSF/IL-5 受体的 βc 亚基的结合。它可用于哮喘、过敏和其他嗜酸性粒细胞疾病的研究。
T17157 TRAF-STOP inhibitor 6877002

CD40-TRAF6 inhibitor

NF-κB NF-κB
TRAF-STOP inhibitor 6877002 (CD40-TRAF6 inhibitor)是一种 CD40-TRAF6 相互作用的选择性抑制剂,可以抑制 RAW 细胞中 NF-κB 活化。TRAF-STOP 6877002 可阻止小鼠动脉粥样硬化的恶化,减少白细胞募集和巨噬细胞的活化,减少动脉粥样硬化斑块中的巨噬细胞增殖。
T9178 (E/Z)-GSK-3β inhibitor 1

GSK-3β inhibitor 1

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
(E/Z)-GSK-3β inhibitor 1 是 (E)-GSK-3β inhibitor 1 和 (Z)-GSK-3β inhibitor 1 的消旋体。它是一种糖原合成酶激酶 3β (GSK-3β)的抑制剂,可其对 GSK-3β 的 IC50=4.9 nM,用于糖尿病的研究。
T10927 Cyt-PTPε Inhibitor-1

Cyt-PTP|A Inhibitor-1

Phosphatase; Src Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
Cyt-PTPε Inhibitor-1 (A Inhibitor-1) 是胞质蛋白酪氨酸磷酸酶 ε 的抑制剂。 Cyt-PTPε Inhibitor-1 阻断 c-Src 的去磷酸化并表现出抗破骨活性。
T36933 Cdk2 Inhibitor II

Cdk2 Inhibitor II,CDK2-IN-3

CDK Cell Cycle/Checkpoint
Cdk2 Inhibitor II 是一种具有选择性和有效性的 CDK2 抑制剂,50 为 60 nM。
T10865L Cot inhibitor-1 hydrochloride

Cot inhibitor-1 hydrochloride(915365-57-0 Free base)

TNF; MAPK Apoptosis; MAPK
Cot inhibitor-1 hydrochloride 是肿瘤进展位点 2 激酶 (IC50 = 28 nM) 的抑制剂,可抑制人全血中 TNF-α 的产生 (IC50 = 5.7 nM)。
TP1523 PKG inhibitor peptide TFA (82801-73-8 free base)

PKG inhibitor peptide TFA

PKA Tyrosine Kinase/Adaptors
PKG inhibitor peptide TFA (82801-73-8 free base) 是 ATP 竞争性 cGMP 依赖性蛋白激酶 (PKG) 的抑制剂。
T22081 FBPase-1 inhibitor-1

Fructose 1,6-bisphosphatase-1 Inhibitor

Others Others
FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) 是一种fructose-1,6-bisphosphatase (FBPase-1)的变构抑制剂。
T22136 PRL-3 Inhibitor I

PRL-3 Inhibitor,BR-1

Phosphatase; Others Metabolism; Others
PRL-3 Inhibitor I (BR-1) 是 PRL-3 抑制剂,IC50=0.9 μM。它在细胞检测中显示降低侵袭性。
T10599 BRAF inhibitor

Raf MAPK
BRAF inhibitor 是B-Raf 抑制剂。
T2649 Menin-MLL inhibitor MI-2

Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2

Apoptosis; Epigenetic Reader Domain; Histone Methyltransferase Apoptosis; Chromatin/Epigenetic
Menin-MLL inhibitor MI-2 (MI2) 抑制Menin-MLL 相互作用,IC50为 446±28 nM。
TP1015 NFAT Inhibitor

VIVIT peptide

Others Others
NFAT Inhibitor (VIVIT peptide) 是NFAT 的细胞渗透性肽抑制剂,能够选择性抑制钙调磷酸酶介导的NFAT 脱磷酸作用。
TP1890L1 MLCK inhibitor peptide 18 acetate

MLCK inhibitor peptide 18 acetate(224579-74-2 free base)

Serine/threonin kinase Cell Cycle/Checkpoint; Metabolism
MLCK inhibitor peptide 18 acetate(224579-74-2 free base) 是肌球蛋白轻链激酶的选择性竞争性抑制剂 (IC50 = 50 nM)。显示出比 CaM 激酶 II 高 4000 倍的选择性,并且不抑制 PKA。细胞可渗透。
T11184 EML4-ALK kinase inhibitor 1

EML4 ALK kinase inhibitor 1,EML4-​ALK kinase inhibitor 1

ALK Angiogenesis; Tyrosine Kinase/Adaptors
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) 是有效的、具有口服活性的类棘皮细胞微管相关蛋白4-间变性淋巴瘤激酶 (EML4-ALK) 的抑制剂,其 IC50 值为 1 nM。
T7541 PTP inhibitor 1

PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮

Phosphatase Metabolism
PTP inhibitor 1 是蛋白酪氨酸磷酸酶 (PTP) 抑制剂,具有抗血管生成作用。
T60108 PDGFR Tyrosine Kinase Inhibitor III

PDGF Receptor Tyrosine Kinase Inhibitor III

PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III)是一种多激酶抑制剂,可抑制 PDGFR、EGFR、FGFR、PKA 和 PKC 等。PDGFR Tyrosine Kinase Inhibitor III 可用于肌萎缩侧索硬化症的研究。
T12502 PLpro inhibitor

5-(乙酰氨基)-2-甲基-N-[(1R)-1-(1-萘基)乙基]苯甲酰胺

SARS-CoV Microbiology/Virology
PLpro inhibitor 是一种木瓜蛋白酶抑制剂,IC50为 2.6 µM,能抑制 SARS-CoV-2 PLpro。
T2159 CaMKP Inhibitor

CaMK Neuroscience
CaMKP Inhibitor 可以抑制 CaMKP。
T10276L AKT Kinase Inhibitor HCl

AKT Kinase Inhibitor HCl(842148-40-7 Free base)

Akt Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
AKT Kinase Inhibitor HCl 是一种 Akt 抑制剂,具有抗肿瘤活性。
T60119 SOD1-Derlin-1 inhibitor-1

SOD1-Derlin-1 Inhibitor 56-20

Others Others
SOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) 是 SOD1-Derlin-1相互作用的抑制剂。SOD1-Derlin-1 inhibitor-1 抑制 SOD1G93A-Derlin-1 复合物,IC50值为 7.11 μM。SOD1-Derlin-1 inhibitor-1 可用于肌萎缩性侧索硬化症的研究。
T5452 Ehp-inhibitor-2

Ephrin Receptor Tyrosine Kinase/Adaptors
Ehp-inhibitor-2 是一种靶向 Eph 受体的 Eph 家族酪氨酸激酶抑制剂。
T36802L Bisubstrate Inhibitor 78 HCl

Bisubstrate Inhibitor 78 HCl(2368247-39-4 Free base)

Others Others
Bisubstrate Inhibitor 78 HCl 是一种 NNMT 抑制剂(IC50 = 1.41 μM),具有潜在的抗癌活性,在 100μM 时抑制HSC-2口腔癌细胞增殖。
T21521L Papain Inhibitor acetate

乙氨酸-乙氨酸-酪氨酸-精氨酸,GGYR,Gly-Gly-Tyr-Arg,Papain Inhibitor acetate (70195-20-9 free base)

Others Others
Papain Inhibitor acetate (Gly-Gly-Tyr-Arg) 是木瓜蛋白酶的亲和配体。
T10463L Bax inhibitor peptide V5 acetate

Bax inhibitor peptide V5 acetate(579492-81-2 free base)

Apoptosis Apoptosis
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) 是一种 Bax 介导的细胞凋亡抑制剂,用于癌症治疗。
T13224 Tubulin inhibitor 6

iHAP1

Microtubule Associated Cytoskeletal Signaling
Tubulin inhibitor 6 (iHAP1) 是一种微管蛋白抑制剂,抑制微管蛋白聚合,IC50为 0.87 μM。它抑制多种癌细胞系,抑制 K562 细胞生长,IC50为 840 nM。

化合物

CPA inhibitor
Cat.No: T10876
Synonym: Carboxypeptidase inhibitor
Target: Carboxypeptidase
Eph inhibitor 2
Cat.No: T5451
Synonym: Ehp-inhibitor-1
Target: Ephrin Receptor
HPGDS inhibitor 1
Cat.No: T1804
Synonym: HPGDS-inhibitor-1
Target: PGE Synthase
USP7/USP47 inhibitor
Cat.No: T4338
Synonym: USP7/47 inhibitor-1
Target: DUB
Aurora kinase inhibitor-3
Cat.No: T5524
Synonym: Aurora Kinase Inhibitor III
Target: Aurora Kinase
MALT1 inhibitor MI-2
Cat.No: T2350
Synonym: MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor)
Target: MALT
GOT1 inhibitor-1
Cat.No: T8766
Synonym: GOT1 inhibitor 2c
Target: Others
PKC-theta inhibitor hcl
Cat.No: T5817
Synonym: PKC-theta inhibitor
Target: PKC
B7/CD28 interaction inhibitor 1
Cat.No: T3189
Synonym: CTLA-4 inhibitor
Target: Others
Raf inhibitor 1
Cat.No: T2074
Synonym: B-Raf inhibitor 1
Target: Raf
SCD1 inhibitor-3
Cat.No: T38683
Synonym: SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a
Target: Dehydrogenase
Src Inhibitor 1
Cat.No: T3593
Synonym: Src Kinase Inhibitor 1,Src-l1
Target: Src
JAK2 Inhibitor V
Cat.No: T3042
Synonym: JAK2 Inhibitor V Z3,Z3
Target: JAK
Tie2 kinase inhibitor 1
Cat.No: T6335
Synonym: Tie2 kinase inhibitor
Target: Tie-2
Multi-kinase inhibitor 1
Cat.No: T4191
Synonym: Multi-kinase inhibitor I
Target: Others, Bcr-Abl, PDGFR, c-Kit
Syk Inhibitor II dihydrochloride
Cat.No: T4391
Synonym: Syk Inhibitor II (hydrochloride)
Target: Others, Tyrosine Kinases, Syk, PKC, BTK
Carboxypeptidase G2 (CPG2) Inhibitor
Cat.No: T10678
Synonym: CPG2 Inhibitor,Carboxypeptidase G2 Inhibitor
Target: Carboxypeptidase
IRAK-1-4 Inhibitor I
Cat.No: T2457
Synonym: IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor
Target: IRAK
HIF-1 inhibitor-4
Cat.No: T67767
Synonym: HIF-1 inhibitor-4
Target: HIF
HIV-1 Inhibitor 18A
Cat.No: T24141
Synonym: HIV-1 Inhibitor-18A
Target: HIV Protease
Raf inhibitor 1 dihydrochloride
Cat.No: T4167
Synonym: B-Raf inhibitor 1 dihydrochloride
Target: Raf
PKCε Inhibitor Peptide acetate
Cat.No: T35827L
Synonym: PKCε Inhibitor Peptide acetate(182683-50-7 Free base)
Target: PKC
LMPTP INHIBITOR 1 hydrochloride
Cat.No: T4491
Synonym: LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base))
Target: Phosphatase
Aurora kinase inhibitor-2
Cat.No: T9040
Synonym: IUN-70219,Aurora Kinase Inhibitor II
Target: Aurora Kinase
EGFR/ErbB-2/ErbB-4 inhibitor-2
Cat.No: T21954
Synonym: EGFR/ErbB2 Inhibitor
Target: EGFR
Lyn peptide inhibitor acetate
Cat.No: TP2008L
Synonym: Lyn peptide inhibitor acetate(222018-18-0 free base)
Target: IL Receptor
TRAF-STOP inhibitor 6877002
Cat.No: T17157
Synonym: CD40-TRAF6 inhibitor
Target: NF-κB
(E/Z)-GSK-3β inhibitor 1
Cat.No: T9178
Synonym: GSK-3β inhibitor 1
Target: GSK-3
Cyt-PTPε Inhibitor-1
Cat.No: T10927
Synonym: Cyt-PTP|A Inhibitor-1
Target: Phosphatase, Src
Cdk2 Inhibitor II
Cat.No: T36933
Synonym: Cdk2 Inhibitor II,CDK2-IN-3
Target: CDK
Cot inhibitor-1 hydrochloride
Cat.No: T10865L
Synonym: Cot inhibitor-1 hydrochloride(915365-57-0 Free base)
Target: TNF, MAPK
PKG inhibitor peptide TFA (82801-73-8 free base)
Cat.No: TP1523
Synonym: PKG inhibitor peptide TFA
Target: PKA
FBPase-1 inhibitor-1
Cat.No: T22081
Synonym: Fructose 1,6-bisphosphatase-1 Inhibitor
Target: Others
PRL-3 Inhibitor I
Cat.No: T22136
Synonym: PRL-3 Inhibitor,BR-1
Target: Phosphatase, Others
BRAF inhibitor
Cat.No: T10599
Synonym:
Target: Raf
Menin-MLL inhibitor MI-2
Cat.No: T2649
Synonym: Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
NFAT Inhibitor
Cat.No: TP1015
Synonym: VIVIT peptide
Target: Others
MLCK inhibitor peptide 18 acetate
Cat.No: TP1890L1
Synonym: MLCK inhibitor peptide 18 acetate(224579-74-2 free base)
Target: Serine/threonin kinase
EML4-ALK kinase inhibitor 1
Cat.No: T11184
Synonym: EML4 ALK kinase inhibitor 1,EML4-​ALK kinase inhibitor 1
Target: ALK
PTP inhibitor 1
Cat.No: T7541
Synonym: PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮
Target: Phosphatase
PDGFR Tyrosine Kinase Inhibitor III
Cat.No: T60108
Synonym: PDGF Receptor Tyrosine Kinase Inhibitor III
Target: PDGFR
PLpro inhibitor
Cat.No: T12502
Synonym: 5-(乙酰氨基)-2-甲基-N-[(1R)-1-(1-萘基)乙基]苯甲酰胺
Target: SARS-CoV
CaMKP Inhibitor
Cat.No: T2159
Synonym:
Target: CaMK
AKT Kinase Inhibitor HCl
Cat.No: T10276L
Synonym: AKT Kinase Inhibitor HCl(842148-40-7 Free base)
Target: Akt
SOD1-Derlin-1 inhibitor-1
Cat.No: T60119
Synonym: SOD1-Derlin-1 Inhibitor 56-20
Target: Others
Ehp-inhibitor-2
Cat.No: T5452
Synonym:
Target: Ephrin Receptor
Bisubstrate Inhibitor 78 HCl
Cat.No: T36802L
Synonym: Bisubstrate Inhibitor 78 HCl(2368247-39-4 Free base)
Target: Others
Papain Inhibitor acetate
Cat.No: T21521L
Synonym: 乙氨酸-乙氨酸-酪氨酸-精氨酸,GGYR,Gly-Gly-Tyr-Arg,Papain Inhibitor acetate (70195-20-9 free base)
Target: Others
Bax inhibitor peptide V5 acetate
Cat.No: T10463L
Synonym: Bax inhibitor peptide V5 acetate(579492-81-2 free base)
Target: Apoptosis
Tubulin inhibitor 6
Cat.No: T13224
Synonym: iHAP1
Target: Microtubule Associated
Cat. No. Product Name Target Signaling Pathways
T3384 Wedelolactone

蟛蜞菊内酯,IKK Inhibitor II

Apoptosis; NF-κB; Lipoxygenase; Caspase Apoptosis; Metabolism; NF-κB; Proteases/Proteasome
Wedelolactone (IKK Inhibitor II) 是来自旱莲草的一种天然产物,通过阻断 IκBα 的磷酸化和降解来抑制细胞中 NF-κB 介导的基因转录,具有抗癌,抗炎和抗氧化活性。
TJS0851 Plantagoside

Others Others
Plantagoside 是α-mannosidase 的非竞争性特异性抑制剂(IC50:5 μM),分离自Plantago asiatica 种子中。
TN1829 Kakkalide

Dehydrogenase Metabolism
Kakkalide 是提取自葛根花中的一种异黄酮。它可以抑制活性氧相关炎症,并改善内皮细胞胰岛素抵抗作用。
T6S2252 Sweroside

Others Others
Sweroside 是分离自Lonicera japonica 中,具有细胞保护、抗骨质疏松和保护肝脏活性。
T3S2019 Lathyrol

Others Others
Lathyrol 是一种具有抗癌功能的天然产物。
T3S1729 Dihydrolycorine

Others Others
Dihydrolycorine 是分离自Lycoris radiate 草药中,是一种真核细胞中蛋白质合成的抑制剂。
T8169 Decursinol

Others Others
Decursinol 是一种分离自Angelica gigas 的根中的、口服具有活性的抗伤害药物。它具有抗肿瘤和抗转移作用。
TN1833 Karacoline

NF-κB NF-κB
Karacoline 是发现于植物Aconitum kusnezoffii 中的一种二萜生物碱,通过 NF-κB 信号通路,抑制椎间盘退变中细胞外基质的降解。
TN6712 yibeissine

Others Others
Yibeissine 是一种甾体生物碱,分离自贝母球茎中。
T3S1850 Bayogenin

Others Others
Bayogenin 是紫花苜蓿皂苷,一定程度上能够抑制糖原磷酸化酶的活性。
T5789 XYLOTRIOSE

Others Others
Xylotriose 是双歧杆菌促生因子,是天然的低聚木糖。
T8212 Dichotomitin

Others Others
Dichotomitin 是一种提取自Belamcanda chinensis 根茎中的异黄酮。
TN1111 Arnidiol

Immunology/Inflammation related Immunology/Inflammation
Arnidiol 是一种五环三萜烯,从Barleria Longiflora LinnF. 中提取得到。
TQ0096 Scabertopin

Others Others
Scabertopin 是一种从地胆草中分离得到倍半萜内酯,具有抗癌和抑菌活性。
T7032 Eupatorin

Others; P450 Metabolism; Others
Eupatorin 是天然存在的黄酮,可捕获 G2-M 细胞周期,激活多个 caspase、细胞色素 C 的释放、多聚 (ADP-核糖) 聚合酶的裂解,促使凋亡细胞死亡。
T8203 Gentianose

Others Others
Gentianose 是一种碳水化合储备物,来源于多年生黄龙胆贮藏根中。
TN2197 Secoisolariciresinol

TNF Apoptosis
Secoisolariciresinol 是一种属于苯丙素类的木脂素。
TN1002 Blumeatin

ROS Immunology/Inflammation
Blumeatin 是从Blumea balsamiferaDC 中分离得到,对 CCl4 和硫代乙酰胺 (TAA) 所致的肝损伤表现出保护活性。
T13350 Wushanicaritin

Others Others
Wushanicaritin 在 DPPH 自由基清除活性测试中显示出显著的抗氧化活性 ,其IC50值为35.3 μM,具有抗肿瘤作用和抗炎活性。
T16943 Stigmastanol

Endogenous Metabolite Metabolism
Stigmastanol 是分离自Hypericum riparium 的 6-氨基衍生物。Hypericum riparium 是属于杜仲科的药用植物。
Fr13711 Tropinone

Others Others
Tropinone 是一种可用作合成 Atropine 中间体的生物碱。
T14961 Chrysene

䓛,屈

Others Others
Chrysene 是高分子量 (HMW) 多环芳烃,有极强的顽固性和致癌性。
T13693 Fibrin

Others Others
Fibrin, the primary constituent of blood clots, is an insoluble protein essential for coagulation. Isolated from bovine blood, this protein is notably synthesized in response to bleeding.
T19231 Cellulase

Others Others
Cellulase 是一种能够催化纤维素和其他碳水化合物水解的酶。
TN1640 Fabiatrin

Others Others
Fabiatrin 是从 Przewalskia tangutica 的正丁醇提取物中分离和鉴定的天然产物。
T6S0234 Toosendanin

Others Others
Toosendanin 是一种从杜鹃花果实皮中提取的三萜,具有杀虫和抗炎活性,可用于研究缓解疼痛。
T5S0661 Koumine

Others Others
Koumine 是一种从钩吻中得到的生物碱,具有高效抗肿瘤活性,在肿瘤细胞中能够提高 Bax/Bcl-2 的蛋白比例和 caspase-3 的表达。在类风湿性关节炎动物模型中,它能够预防关节炎的发展。它具有抗焦虑、抗应激、抗银屑病作用,也可用于缓解疼痛的研究。
T3S2027 Rubusoside

Others Others
Rubusoside 是天然的增溶剂及甜味剂,具有良好的抗血管新生和抗过敏药的特性。
TN2058 Persicogenin

Anti-infection Microbiology/Virology
Persicogenin 是分离自 Rhus retinorrhoea 中,具有抗癌作用。
T3A2414 Manninotriose

Others Others
Manninotriose 是小野芝麻主要的碳水化合物(Lamium 象草,唇形科)。
TN1081 Hirsuteine

Dopamine Receptor GPCR/G Protein; Neuroscience
Hirsuteine 是提取自钩藤属植物中的吲哚生物碱。它可阻断离子渗透通过烟碱受体通道复合物,非竞争性地拮抗烟碱介导的多巴胺释放。
T8161 Vicine

Others Others
Vicine 是一种主要存在于蚕豆中的生物碱糖苷,对人体有毒,可引起溶血性贫血。
TN1816 Kadsurin

Antioxidant oxidation-reduction
Kadsurin 是一种提取自异形南五味子茎中的天然产物,能够显著降低小鼠肝脏中CCL4诱导的脂质过氧化产物(例如TBA-RS、共轭二烯和荧光产物)。
T3928 Neoliquiritin

Others Others
Neoliquiritin 是从甘草 Glycyrrhiza uralensis 分离得到,具有抗炎作用。它可能具有细胞毒性和肿瘤特异性。
T6S1657 Paeonolide

Others Others
Paeonolide 是一种广泛存在于 Paeonia 属植物根中的植物糖苷,含有一个非还原性末端 α-1-阿拉伯吡喃糖苷。
T3817 Darutigenol

Others Others
Darutigenol 是一种戊二萜,从Siegesbecikia orientalis L.中分离得到。
T7033 Rosmanol

Antioxidant; COX Immunology/Inflammation; Neuroscience; oxidation-reduction
Rosmanol 能够显著抑制脂多糖诱导的 INOS、COX-2 的表达,抑制低密度脂蛋白的氧化,并具有抗炎作用。
T6S1049 Wilforine

ATPase Membrane transporter/Ion channel
Wilforine 是一倍半萜吡啶化合物,T. wilfordii 植物中的重要生物活性化合物,可有效治疗特发性肺纤维化。它具有抗炎和杀虫活性。
T4953 Neotuberostemonine

NOS Immunology/Inflammation
Neotuberostemonine 是一种结核分枝杆菌根中主要的止咳生物碱,能够阻碍巨噬细胞的募集和活化,从而减轻博来霉素 (Bleomycin) 诱导的肺纤维化。
T5747 ISOBERGAPTEN

Others Others
Isobergapten 是一种化感抑制剂,分离自Hevacleum laciniatum 种子。
TN3548 Bulleyanin

Others Others
Bulleyanin 是从 isodon species (Labiatae) 中分离出来的一种物质。
T39049 Yubeinine

Others Others
Yubeinine 是一种生物碱类天然产物,可以起到气管松弛作用。
TN1785 Isomagnolone

Others Others
Isomagnolone 是一种分离自八角茴香中的天然产物,具有抗炎作用。
TN1455 Bryodulcosigenin

Immunology/Inflammation related Immunology/Inflammation
Bryodulcosigenin 是一种 Bryoniadioica 根的提取物,具有抗炎活性。
T8195 Lotusine

Others Others
Lotusine 是一种提取自Nelumbo nucifera Gaertn 的绿色种胚中的纯生物碱。它能够作用于心肌中动作电位及心脏浦肯野纤维缓慢内向电流。
TN1028 Militarine

Others Others
Militarine 是一种糖苷化合物,分离自 Bletilla striata,能够抑制植物生长。
T3S0693 Blinin

Others Others
Blinin 是一种二萜,分离自植物 Conyza blinii 中。
T8194 Isoflavone

Antioxidant oxidation-reduction
Isoflavone 是大豆植物雌激素和生物活性成分,存在于大豆、青豆、花生、鹰嘴豆和苜蓿等几种重要的豆类作物中。
TN1065 Hirsutine

Apoptosis Apoptosis
Hirsutine 是一种来自钩藤的吲哚生物碱,可诱导细胞凋亡,是一种登革热病毒抑制剂,且毒性低。它具有抗癌、心脏保护、抗高血压、抗心律失常和血管舒张活性。
T5813 BYAKANGELICIN

Reductase Endocrinology/Hormones; Metabolism
Byakangelicin 是发现于当归根中的一种活性化合物,可作为调节剂,改善各种活性化合物 (Umb,Cur 和 Dox) 的脑积累,增强研究效果。它提高所有PXR 靶基因 (如MDR1) 的表达,并广泛的诱导药物-药物相互作用。它可抑制性激素的作用,可能会增加内源激素的分解代谢。
------------------------ 更多 ------------------------

天然产物

Wedelolactone
Cat.No: T3384
Synonym: 蟛蜞菊内酯,IKK Inhibitor II
Target: Apoptosis, NF-κB, Lipoxygenase, Caspase
Plantagoside
Cat.No: TJS0851
Synonym:
Target: Others
Kakkalide
Cat.No: TN1829
Synonym:
Target: Dehydrogenase
Sweroside
Cat.No: T6S2252
Synonym:
Target: Others
Lathyrol
Cat.No: T3S2019
Synonym:
Target: Others
Dihydrolycorine
Cat.No: T3S1729
Synonym:
Target: Others
Decursinol
Cat.No: T8169
Synonym:
Target: Others
Karacoline
Cat.No: TN1833
Synonym:
Target: NF-κB
yibeissine
Cat.No: TN6712
Synonym:
Target: Others
Bayogenin
Cat.No: T3S1850
Synonym:
Target: Others
XYLOTRIOSE
Cat.No: T5789
Synonym:
Target: Others
Dichotomitin
Cat.No: T8212
Synonym:
Target: Others
Arnidiol
Cat.No: TN1111
Synonym:
Target: Immunology/Inflammation related
Scabertopin
Cat.No: TQ0096
Synonym:
Target: Others
Eupatorin
Cat.No: T7032
Synonym:
Target: Others, P450
Gentianose
Cat.No: T8203
Synonym:
Target: Others
Secoisolariciresinol
Cat.No: TN2197
Synonym:
Target: TNF
Blumeatin
Cat.No: TN1002
Synonym:
Target: ROS
Wushanicaritin
Cat.No: T13350
Synonym:
Target: Others
Stigmastanol
Cat.No: T16943
Synonym:
Target: Endogenous Metabolite
Tropinone
Cat.No: Fr13711
Synonym:
Target: Others
Chrysene
Cat.No: T14961
Synonym: 䓛,屈
Target: Others
Fibrin
Cat.No: T13693
Synonym:
Target: Others
Cellulase
Cat.No: T19231
Synonym:
Target: Others
Fabiatrin
Cat.No: TN1640
Synonym:
Target: Others
Toosendanin
Cat.No: T6S0234
Synonym:
Target: Others
Koumine
Cat.No: T5S0661
Synonym:
Target: Others
Rubusoside
Cat.No: T3S2027
Synonym:
Target: Others
Persicogenin
Cat.No: TN2058
Synonym:
Target: Anti-infection
Manninotriose
Cat.No: T3A2414
Synonym:
Target: Others
Hirsuteine
Cat.No: TN1081
Synonym:
Target: Dopamine Receptor
Vicine
Cat.No: T8161
Synonym:
Target: Others
Kadsurin
Cat.No: TN1816
Synonym:
Target: Antioxidant
Neoliquiritin
Cat.No: T3928
Synonym:
Target: Others
Paeonolide
Cat.No: T6S1657
Synonym:
Target: Others
Darutigenol
Cat.No: T3817
Synonym:
Target: Others
Rosmanol
Cat.No: T7033
Synonym:
Target: Antioxidant, COX
Wilforine
Cat.No: T6S1049
Synonym:
Target: ATPase
Neotuberostemonine
Cat.No: T4953
Synonym:
Target: NOS
ISOBERGAPTEN
Cat.No: T5747
Synonym:
Target: Others
Bulleyanin
Cat.No: TN3548
Synonym:
Target: Others
Yubeinine
Cat.No: T39049
Synonym:
Target: Others
Isomagnolone
Cat.No: TN1785
Synonym:
Target: Others
Bryodulcosigenin
Cat.No: TN1455
Synonym:
Target: Immunology/Inflammation related
Lotusine
Cat.No: T8195
Synonym:
Target: Others
Militarine
Cat.No: TN1028
Synonym:
Target: Others
Blinin
Cat.No: T3S0693
Synonym:
Target: Others
Isoflavone
Cat.No: T8194
Synonym:
Target: Antioxidant
Hirsutine
Cat.No: TN1065
Synonym:
Target: Apoptosis
BYAKANGELICIN
Cat.No: T5813
Synonym:
Target: Reductase
--------- 更多 ---------
Cat. No. Product Name Species Expression System
TMPY-04815 C1 inhibitor Protein, Rat, Recombinant (His)

serpin peptidase inhibitor, clade G (C1 inhibit...

Rat HEK293
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides ...
TMPY-01183 C1 inhibitor Protein, Human, Recombinant (His)

serpin peptidase inhibitor, clade G (C1 inhibit...

Human HEK293
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides ...
TMPY-01030 TFPI Protein, Human, Recombinant (His)

TFPI1,tissue factor pathway inhibitor (lipoprotein-...

Human HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. With its Kunitz domains, TFPI exhibits significant homology with human inter-alpha-trypson inhibitor and bovin basic pancreatic trypsin inhibitor. TFPI is the natural inhibitor of TF coagulant and signaling activities. The importance of TFPI in the regulation of blood coagulation is...
TMPY-01174 DKK1 Protein, Rhesus, Recombinant (N256Q, His)

dickkopf WNT signaling pathway inhibitor 1

Rhesus HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majori...
TMPY-01121 DKK3 Protein, Mouse, Recombinant (His)

dickkopf WNT signaling pathway inhibitor 3,C87148,A...

Mouse HEK293
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its...
TMPY-04811 DKK1 Protein, Mouse, Recombinant (His)

dickkopf WNT signaling pathway inhibitor 1,mdkk-1

Mouse HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majori...
TMPY-00775 DKK1 Protein, Human, Recombinant (His)

dickkopf WNT signaling pathway inhibitor 1,SK,DKK-1

Human HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majori...
TMPY-02731 SPINK4 Protein, Mouse, Recombinant (hFc)

MPGC60,serine peptidase inhibitor, Kazal type 4,RP2...

Mouse HEK293
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activit...
TMPY-06074 B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)

V-set domain containing T cell activation inhibitor...

Cynomolgus,Rhesus HEK293
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands on T lymphocytes. They provide costimulatory signals that regulate T cell responses. A soluble form of B7H4 has also been detected. B7X / VTCN1 / B7H4 negatively regulates T-cell-mediated immune response by i...
TMPY-01474 PAI-1 Protein, Human, Recombinant (His)

PAI,SERPINE1,PAI-1,serpin peptidase inhibitor, clad...

Human HEK293
Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SerpinE1 and PLANH1, is a secreted glycoprotein that belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SerpinE1 are the cause of plasminogen activator inhibitor-1 def...
TMPY-05322 B7-H4 Protein, Mouse, Recombinant (His)

BC032925,B7h4,B7x,V-set domain containing T cell activation ...

Mouse HEK293
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands on T lymphocytes. They provide costimulatory signals that regulate T cell responses. A soluble form of B7H4 has also been detected. B7X / VTCN1 / B7H4 negatively regulates T-cell-mediated immune response by i...
TMPY-00915 Serpin A1 Protein, Human, Recombinant (His)

PRO2275,SerpinA1,serpin peptidase inhibitor, clade ...

Human HEK293
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antitrypsin is mainly produced in the liver and acts as an antiprotease. Its principal function is to inactivate neutrophil elastase, preventing tissue damage. SerpinA1 (alpha1-antitrypsin), an acute phase protein and the classical neutrophil elastase inhibitor, is localized within li...
TMPY-00916 Antithrombin III Protein, Human, Recombinant (His)

AT3D,THPH7,ATIII,AT3,Serpin C1,MGC22579,serpin peptidase

Human HEK293
SerpinC1, also known as antithrombin III (AT III), is a member of the serpin superfamily of serine protease inhibitors, and has been found to be a marker for disseminated intravascular coagulation (DIC) and to be of prognostic significance in septic patients. SerpinC1 synthesized in the liver is the principal plasma serpin of blood coagulation proteases and inhibits thrombin and other factors such as Xa by the formation of covalently linked complexes. Thus it is one of the most important coagula...
TMPJ-00603 TL1A Protein, Mouse, Recombinant

TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V...

Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ...
TMPJ-00916 TIMP-2 Protein, Mouse, Recombinant (His)

metalloproteinase inhibitor 2,Tissue inhibitor<...

Mouse Human Cells
Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP‑1, TIMP‑2, TIMP‑3, and TIMP‑4. The TIMP-2 is detected in testis, retina, hippocampus and cerebral cortex. The function of TIMP 2 protein is to inhibit MMPs non covalently by the formation of binary complexes. Complexes with metalloproteinases (such as collagenases) and irreversi...
TMPY-03524 B7-H4 Protein, Human, Recombinant (His)

PRO1291,B7X,B7H4,B7-H4,VCTN1,B7S1,B7h.5,V-set domain contain...

Human HEK293
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands on T lymphocytes. They provide costimulatory signals that regulate T cell responses. A soluble form of B7H4 has also been detected. B7X / VTCN1 / B7H4 negatively regulates T-cell-mediated immune response by i...
TMPH-00554 Trypsin inhibitor DE-3 Protein, Erythrina caffra, Recombinant (His)

Erythrina caffra Yeast
Part of the tripartite complex that is required for the CDT activity. CdtC, along with CdtA, probably forms a heterodimeric subunit required for the delivery of CdtB.
TMPY-02912 TIMP-1 Protein, Rat, Recombinant

TIMP metallopeptidase inhibitor 1

Rat HEK293
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly ...
TMPY-03876 PTGFRN Protein, Cynomolgus, Recombinant (His)

prostaglandin F2 receptor inhibitor

Cynomolgus HEK293
EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT. EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. EWI-F expression positively correlates with the metastatic status of hLT, and that the upregulation of EWI-F expression could be one of the mechanisms underlying the loss of CD9 in solid tumours.
TMPJ-00490 Serpin A5 Protein, Human, Recombinant (His)

Plasminogen Activator Inhibitor 3,Acrosomal Serine ...

Human Human Cells
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes o...
TMPJ-01289 TIMP-4 Protein, Human, Recombinant (His)

TIMP4,TIMP-4,Metalloproteinase inhibitor 4,Tissue <...

Human Human Cells
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
TMPY-05179 TFPI Protein, Human, Recombinant (His), Biotinylated

TFI,TFPI1,EPI,LACI,tissue factor pathway inhibitor ...

Human HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. With its Kunitz domains, TFPI exhibits significant homology with human inter-alpha-trypson inhibitor and bovin basic pancreatic trypsin inhibitor. TFPI is the natural inhibitor of TF coagulant and signaling activities. The importance of TFPI in the regulation of blood coagulation is...
TMPJ-00733 SPINK1 Protein, Human, Recombinant (His)

PSTI,Pancreatic Secretory Trypsin Inhibitor,TATI,Se...

Human Human Cells
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). Recombinant SPINK1 protein (rSPINK1) stimulated cell proliferation in benign RWPE ...
TMPJ-00625 Serpin E1 Protein, Mouse, Recombinant (His)

Pai1,Planh1,Plasminogen activator inhibitor 1,Serpi...

Mouse Human Cells
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
TMPY-05800 IKB beta/NFKBIB Protein, Human, Recombinant (GST)

NFKB inhibitor β,NFKB inhibitor beta,TRIP9...

Human E. coli
NFKBIB (NFKB Inhibitor Beta) is a Protein Coding gene. The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. NF-kappaB regulation involves the inhibitor pr...
TMPY-00163 SPINK2 Protein, Human, Recombinant (hFc)

serine peptidase inhibitor, Kazal type 2 (acrosin-t...

Human HEK293
Human serine proteinase inhibitor Kazal-type 2 (SPINK2) functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. The expression of SPINK2 is closely related to cancer such as lymphomas, in that a high transcript level of SPINK2 in patients with primary cutaneous follicle center cell lymphomas ...
TMPJ-00101 TIMP-2 Protein, Human, Recombinant (His)

Tissue Inhibitor of Metalloproteinases 2,TIMP2,CSC-...

Human Human Cells
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3, and TIMP-4. Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and i...
TMPJ-00972 CDKN1B Protein, Human, Recombinant (His)

KIP1,CDKN1B,Cyclin-Dependent Kinase Inhibitor p27,C...

Human E. coli
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skeletal muscle. CDKN1B is a potent inhibitor of Cyclin E- and Cyclin A-CDK2 complexes. CDKN1B forms a complex with Cyclin Type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. In addition, CDKN1B acts as an inhibitor or an ...
TMPY-00928 TFPI Protein, Mouse, Recombinant (His)

AW552122,A630013F22Rik,tissue factor pathway inhibitor

Mouse HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. With its Kunitz domains, TFPI exhibits significant homology with human inter-alpha-trypson inhibitor and bovin basic pancreatic trypsin inhibitor. TFPI is the natural inhibitor of TF coagulant and signaling activities. The importance of TFPI in the regulation of blood coagulation is...
TMPJ-01383 Serpin A10 Protein, Human, Recombinant (His)

PZI,Protein Z-Dependent Protease Inhibitor,Serpin A...

Human Human Cells
Serpin A10 is a secreted protein that belongs to the serpin family. It is predominantly expressed in the liver and secreted in the plasma. Its phosphorylation sites are present in the extracelllular medium. It inhibits factors Xa and XIa of the coagulation cascade in the presence of protein Z, calcium, and phospholipid. Mutations in SERPINA10 are associated with venous thrombosis.
TMPY-05797 DKK1 Protein, Rat, Recombinant (His)

dickkopf WNT signaling pathway inhibitor 1

Rat HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majori...
TMPJ-00931 Serpin A4 Protein, Human, Recombinant (His)

Kallistatin,Peptidase Inhibitor 4,KST,Kallikrein

Human Human Cells
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition,...
TMPJ-01069 Serpin A1e Protein, Mouse, Recombinant (His)

Dom5,α-1-antitrypsin 1-5,Serpina1e,Spi1-5,Serine protease

Mouse Human Cells
Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein ...
TMPJ-01064 Serpin G1 Protein, Mouse, Recombinant (His)

Serping1,Plasma protease C1 inhibitor,C1 Inh,C1 est...

Mouse Human Cells
SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation. SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. SERPIN G1 prevents the proteolytic cleavage of later...
TMPY-03127 BAMBI Protein, Mouse, Recombinant (hFc)

2610003H06Rik,BMP and activin membrane-bound inhibitor

Mouse HEK293
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellular domain and a short cytoplasmic region that share sequence similarities with type 1 receptors, whose members have functions in signal transduction in various developing and pathological processes. BAMBI competes with the type 1 receptor, a receptor of the transforming growth f...
TMPY-02187 SEMA5A Protein, Human, Recombinant (hFc)

SEMAF,serpin peptidase inhibitor, clade F,semF

Human HEK293
Semaphorins are secreted, transmembrane, and GPI-linked proteins, defined by cysteine-rich semaphorin protein domains, that have important roles in a variety of tissues. Humans have 2 semaphorins, Drosophila has five, and two are known from DNA viruses. Semaphorins are found in nematodes and crustaceans but not in non-animals. They are grouped into eight classes on the basis of phylogenetic tree analyses and the presence of additional protein motifs. Semaphorins have been implicated in diverse d...
TMPY-01175 DKK1 Protein, Rhesus, Recombinant (N256Q, mFc)

dickkopf WNT signaling pathway inhibitor 1

Rhesus HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majori...
TMPY-02981 ING5 Protein, Human, Recombinant (GST)

p28ING5,inhibitor of growth family, member 5

Human E. coli
ING5 belongs to the ING family. It contains 1 PHD-type zinc finger and is a component of the HBO1 complex. HBO1 complex has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15, PHF16, and PHF17. ING5 also is a component of the MOZ/MORF complex which is composed at least of ING5, KAT6A, KAT6B, MEAF6, and one of BRP...
TMPY-02559 PAI-1 Protein, Rat, Recombinant (His)

serpin peptidase inhibitor, clade E (nexin, plasmin...

Rat HEK293
Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SerpinE1 and PLANH1, is a secreted glycoprotein that belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SerpinE1 are the cause of plasminogen activator inhibitor-1 def...
TMPH-00520 Host-nuclease inhibitor protein gam Protein, Enterobacteria phage lambda, Recombinant (His & Myc)

Escherichia phage lambda E. coli
Catalyzes the hydroxylation of 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
TMPJ-00685 BAI3 Protein, Human, Recombinant (His)

BAI3,KIAA0550,Brain-Specific Angiogenesis Inhibitor...

Human Human Cells
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-...
TMPJ-00243 Serpin B6 Protein, Human, Recombinant (E. coli, His)

CAP,PI6,SERPINB6,Placental Thrombin Inhibitor,Cytop...

Human E. coli
Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. In addition, Serpin B6 may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and se...
TMPY-00397 ITIH3 Protein, Human, Recombinant (hFc)

H3P,SHAP,inter-α-trypsin inhibitor heavy chain 3,in...

Human HEK293
ITIH3 (Inter-Alpha-Trypsin Inhibitor Heavy Chain 3) is a Protein Coding gene. This gene encodes the heavy chain subunit of the pre-alpha-trypsin inhibitor complex. This complex may stabilize the extracellular matrix through its ability to bind hyaluronic acid. ITIH3 is involved in the stabilization of the extracellular matrix. A polymorphism (rs2535629) of ITIH3 showed the strongest association signal with susceptibility to psychiatric disorders in Caucasian populations. Common single nucleotide...
TMPJ-00452 Serpin A1a Protein, Mouse, Recombinant (His)

Alpha-1-antitrypsin 1-1, Alpha-1 protease inhibitor...

Mouse Human Cells
Serpin A1a is also known as alpha-1-antitrypsin, is a member of the serpin superfamily of serine proteinase inhibitors that are involved in the regulation of a number of proteolytic processes. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.
TMPJ-00502 Serpin G1 Protein, Human, Recombinant (His)

C1-Inhibiting Factor,Serpin G1,SERPING1,C1 Esterase Inhi...

Human Human Cells
As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein. It is the largest member among the serpin class of proteins. Remarkably, Serpin G1 has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of Serpin G1 provides the inhibitory activity. The N-terminal domain ...
TMPY-00629 PAI-1 Protein, Rat, Recombinant (hFc)

serpin peptidase inhibitor, clade E (nexin, plasmin...

Rat HEK293
Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SerpinE1 and PLANH1, is a secreted glycoprotein that belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SerpinE1 are the cause of plasminogen activator inhibitor-1 def...
TMPJ-00963 CDKN2C Protein, Human, Recombinant (His)

Cyclin-Dependent Kinase 4 Inhibitor C,p18-INK4c,CDK...

Human E. coli
Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis,...
TMPY-01868 TIMP-2 Protein, Human, Recombinant

CSC-21K,DDC8,TIMP metallopeptidase inhibitor 2

Human HEK293
Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. The TIMP family encompasses four members (TIMP1-4), and they inhibit most MMPs by forming non-covalent binary complex. TIMP2 is a 22 kDa non N-glycosylated protein expressed by a variety of cell types, and plays a unique role among TIMP family members owing to its functions to regulate cellular response...
TMPY-00933 TIMP-2 Protein, Human, Recombinant (hFc)

TIMP metallopeptidase inhibitor 2,DDC8,CSC-21K

Human HEK293
Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. The TIMP family encompasses four members (TIMP1-4), and they inhibit most MMPs by forming non-covalent binary complex. TIMP2 is a 22 kDa non N-glycosylated protein expressed by a variety of cell types, and plays a unique role among TIMP family members owing to its functions to regulate cellular response...
TMPY-00266 PEDF Protein, Rat, Recombinant (His)

serpin peptidase inhibitor, clade F,member 1

Rat HEK293
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-a...
------------------------ 更多 ------------------------

重组蛋白

C1 inhibitor Protein, Rat, Recombinant (His)
Cat.No: TMPY-04815
Species: Rat
Expression System: HEK293
C1 inhibitor Protein, Human, Recombinant (His)
Cat.No: TMPY-01183
Species: Human
Expression System: HEK293
TFPI Protein, Human, Recombinant (His)
Cat.No: TMPY-01030
Species: Human
Expression System: HEK293
DKK1 Protein, Rhesus, Recombinant (N256Q, His)
Cat.No: TMPY-01174
Species: Rhesus
Expression System: HEK293
DKK3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01121
Species: Mouse
Expression System: HEK293
DKK1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04811
Species: Mouse
Expression System: HEK293
DKK1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00775
Species: Human
Expression System: HEK293
SPINK4 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02731
Species: Mouse
Expression System: HEK293
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-06074
Species: Cynomolgus,Rhesus
Expression System: HEK293
PAI-1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01474
Species: Human
Expression System: HEK293
B7-H4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05322
Species: Mouse
Expression System: HEK293
Serpin A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00915
Species: Human
Expression System: HEK293
Antithrombin III Protein, Human, Recombinant (His)
Cat.No: TMPY-00916
Species: Human
Expression System: HEK293
TL1A Protein, Mouse, Recombinant
Cat.No: TMPJ-00603
Species: Mouse
Expression System: E. coli
TIMP-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00916
Species: Mouse
Expression System: Human Cells
B7-H4 Protein, Human, Recombinant (His)
Cat.No: TMPY-03524
Species: Human
Expression System: HEK293
Trypsin inhibitor DE-3 Protein, Erythrina caffra, Recombinant (His)
Cat.No: TMPH-00554
Species: Erythrina caffra
Expression System: Yeast
TIMP-1 Protein, Rat, Recombinant
Cat.No: TMPY-02912
Species: Rat
Expression System: HEK293
PTGFRN Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03876
Species: Cynomolgus
Expression System: HEK293
Serpin A5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00490
Species: Human
Expression System: Human Cells
TIMP-4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01289
Species: Human
Expression System: Human Cells
TFPI Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05179
Species: Human
Expression System: HEK293
SPINK1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00733
Species: Human
Expression System: Human Cells
Serpin E1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00625
Species: Mouse
Expression System: Human Cells
IKB beta/NFKBIB Protein, Human, Recombinant (GST)
Cat.No: TMPY-05800
Species: Human
Expression System: E. coli
SPINK2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00163
Species: Human
Expression System: HEK293
TIMP-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00101
Species: Human
Expression System: Human Cells
CDKN1B Protein, Human, Recombinant (His)
Cat.No: TMPJ-00972
Species: Human
Expression System: E. coli
TFPI Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00928
Species: Mouse
Expression System: HEK293
Serpin A10 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01383
Species: Human
Expression System: Human Cells
DKK1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-05797
Species: Rat
Expression System: HEK293
Serpin A4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00931
Species: Human
Expression System: Human Cells
Serpin A1e Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01069
Species: Mouse
Expression System: Human Cells
Serpin G1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01064
Species: Mouse
Expression System: Human Cells
BAMBI Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03127
Species: Mouse
Expression System: HEK293
SEMA5A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02187
Species: Human
Expression System: HEK293
DKK1 Protein, Rhesus, Recombinant (N256Q, mFc)
Cat.No: TMPY-01175
Species: Rhesus
Expression System: HEK293
ING5 Protein, Human, Recombinant (GST)
Cat.No: TMPY-02981
Species: Human
Expression System: E. coli
PAI-1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02559
Species: Rat
Expression System: HEK293
Host-nuclease inhibitor protein gam Protein, Enterobacteria phage lambda, Recombinant (His & Myc)
Cat.No: TMPH-00520
Species: Escherichia phage lambda
Expression System: E. coli
BAI3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00685
Species: Human
Expression System: Human Cells
Serpin B6 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPJ-00243
Species: Human
Expression System: E. coli
ITIH3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00397
Species: Human
Expression System: HEK293
Serpin A1a Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00452
Species: Mouse
Expression System: Human Cells
Serpin G1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00502
Species: Human
Expression System: Human Cells
PAI-1 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-00629
Species: Rat
Expression System: HEK293
CDKN2C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00963
Species: Human
Expression System: E. coli
TIMP-2 Protein, Human, Recombinant
Cat.No: TMPY-01868
Species: Human
Expression System: HEK293
TIMP-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00933
Species: Human
Expression System: HEK293
PEDF Protein, Rat, Recombinant (His)
Cat.No: TMPY-00266
Species: Rat
Expression System: HEK293
--------- 更多 ---------
共10000条,每页50条 1 2 3 4 5 ... 200
联系我们
400-820-0310

上海市静安区江场三路238号8楼