E3 Ligase Ligand-Linker Conjugate

E3 Ligase Ligand-Linker Conjugate consists of the ligand and linker from the E3 ubiquitin ligase, enabling the synthesis of PROTAC with target protein ligands. The E3 Ligase Ligand portion is often based on von Hippel-Lindau (VHL), MDM2, Cereblon (CRBN) , etc., while the linker portion commonly employs PEG chains, alkyl chains, or rigid aromatic rings. E3 Ligase Ligand-Linker Conjugate serves as a crucial tool for developing highly efficient and selective protein degradation agents.