Abscisic Acid

Name: Abscisic Acid
Brand: TargetMol
SKU: T6368
Price: 252 CNY
Availability: InStock
Rating: 5 (10 reviews)

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纯度: 99.73%

货号 T6368Cas号 21293-29-8

别名 Dormin, Abscisin II, Abscisic Acid (Dormin), (+)-脱落酸, (+)-ABA

Abscisic Acid (Dormin) 是具有口服活性的植物激素，存在于蔬菜和水果中，也是内源性的哺乳动物激素。它是生长抑制剂，可以调节植物生长发育。他抑制质子泵，并导致 Ca2+依赖性的质膜去极化。它是 LANCL2 的天然配体，属于胰岛素敏感化合物，在糖尿病前期，2 型糖尿病和代谢综合征的研究中具有价值。

Abscisic Acid

一键复制产品信息

很棒

纯度: 99.73%

货号 T6368 别名 Dormin, Abscisin II, Abscisic Acid (Dormin), (+)-脱落酸, (+)-ABACas号 21293-29-8

规格	价格	库存
1 mg	¥ 252	现货
5 mg	¥ 569	现货
10 mg	¥ 828	现货
25 mg	¥ 1,360	现货
50 mg	¥ 1,990	现货
100 mg	¥ 2,980	现货
200 mg	¥ 4,280	现货
1 mL x 10 mM (in DMSO)	¥ 598	现货

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产品介绍

Abscisic Acid AI Summary

Abscisic Acid exhibits significant bioactivity across various assays, demonstrating its potential as an inhibitor of multiple biological processes. It shows potent inhibitory effects on seed germination and seedling elongation in species such as Arabidopsis thaliana, Lactuca sativa, Spinacia oleracea, and Oryza sativa, with IC50 values in the low nanomolar range for some species. Specifically, it inhibits barley seeds' alpha-amylase induction with an IC50 of 501.19 nM and cress seed germination at 977.24 nM. Additionally, it affects lettuce seed germination and rice seedling elongation with IC50 values of 12000.0 nM and 2000.0 nM, respectively. In biochemical contexts, Abscisic Acid inhibits ABI1 and ABI2 with IC50 values of 60.0 nM and 70.0 nM, respectively, and increases intracellular cAMP levels in human granulocytes, showing 35.0% activity at 1 uM. It also demonstrates antineuroinflammatory properties, inhibiting LPS-induced nitric oxide production in mouse N9 cells with an IC50 of 68020.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.
别名	Dormin, Abscisin II, Abscisic Acid (Dormin), (+)-脱落酸, (+)-ABA

化学信息

分子量	264.32
分子式	C₁₅H₂₀O₄
CAS No.	21293-29-8
Smiles	C\C(\C=C\[C@@]1(O)C(C)=CC(=O)CC1(C)C)=C\C(O)=O
密度	1.193 g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 252 mg/mL (953.39 mM), Sonication is recommended.

Ethanol: 49 mg/mL (185.38 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (18.92 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7833 mL	18.9165 mL	37.8329 mL	189.1646 mL
5 mM	0.7567 mL	3.7833 mL	7.5666 mL	37.8329 mL
10 mM	0.3783 mL	1.8916 mL	3.7833 mL	18.9165 mL
20 mM	0.1892 mL	0.9458 mL	1.8916 mL	9.4582 mL
50 mM	0.0757 mL	0.3783 mL	0.7567 mL	3.7833 mL
100 mM	0.0378 mL	0.1892 mL	0.3783 mL	1.8916 mL