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别名 N-苄基-对甲苯磺酸胺, N-Tosylbenzylamine, N-Benzyl-p-toluenesulfonamide
BTS (N-Tosylbenzylamine) 是一种选择性骨骼肌肌球蛋白 II 亚片段 1 (S1) ATPase 活性抑制剂,可特异性抑制骨骼肌快速纤维的收缩。它对肌动蛋白和 Ca2+刺激的肌球蛋白 S1 ATPase 的 IC50值约为 5 µM。

BTS (N-Tosylbenzylamine) 是一种选择性骨骼肌肌球蛋白 II 亚片段 1 (S1) ATPase 活性抑制剂,可特异性抑制骨骼肌快速纤维的收缩。它对肌动蛋白和 Ca2+刺激的肌球蛋白 S1 ATPase 的 IC50值约为 5 µM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 g | ¥ 99 | 现货 | |
| 1 mL x 10 mM (in DMSO) | ¥ 108 | 现货 |
BTS 相关产品
| 产品描述 | BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) . |
| 靶点活性 | Myosin S1 ATPase (Ca2+ stimulated):5 μM |
| 体内活性 | BTS is remarkably specific, as it was much less effective in suppressing contraction in rat myocardial or rabbit slow-twitch muscle, and did not inhibit platelet myosin II.?The isolation of BTS and the recently discovered Eg5 kinesin inhibitor, monastrol, suggests that motor proteins may be potential targets for therapeutic applications. |
| 别名 | N-苄基-对甲苯磺酸胺, N-Tosylbenzylamine, N-Benzyl-p-toluenesulfonamide |
| 分子量 | 261.34 |
| 分子式 | C14H15NO2S |
| CAS No. | 1576-37-0 |
| Smiles | CC1=CC=C(C=C1)S(=O)(=O)NCC1=CC=CC=C1 |
| 密度 | 1.204 g/cm3 |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| 溶解度信息 | DMSO: 75 mg/mL (286.98 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| 体内实验配方 | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.65 mM), Sonication is recommended. 请按顺序添加溶剂,在添加下一种溶剂之前,尽可能使溶液澄清。如有必要,可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考,体内配方并不是绝对的,请根据不同情况进行调整。 | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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