规格

价格

库存

数量

1 mg

¥ 695

现货

5 mg

¥ 1,730

现货

10 mg

¥ 2,590

现货

25 mg

¥ 4,290

现货

1 mL x 10 mM (in DMSO)

¥ 1,780

现货

生物活性

产品描述	(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.
体外活性	Oxypeucedanin 对正常成纤维细胞和敏感的亲本小鼠淋巴瘤细胞展现了边缘毒性；对多药耐药淋巴瘤细胞的毒性更低。Oxypeucedanin 表现出中等的多药耐药（MDR）逆转活性。在方格实验中，oxypeucedanin 和 heraclenin 与 doxorubicin 有轻微的协同效应。这些化合物可能增强标准化疗化合物 doxorubicin 的细胞毒效应。
细胞实验	Pure compounds were isolated from the extract of aerial parts of the plant by chromatographic methods.Bioactivities were tested on multidrug resistant and sensitive mouse T-lymphoma cell lines.The inhibition of the cancer MDR efflux pump ABCB1 was evaluated by flow cytometry (at 2 and 20 μM).A checkerboard microplate method was applied to study the interactions of furocoumarins and doxorubicin.Toxicity was studied using normal murine NIH/3T3 fibroblasts.
别名	水合氧化前胡素, OXYPEUCEDANIN HYDRATE

化学信息

分子量	304.29
分子式	C₁₆H₁₆O₆
CAS No.	133164-11-1
Smiles	CC(C)(O)[C@@H](O)COc1c2ccoc2cc2oc(=O)ccc12
密度	1.386 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 55 mg/mL (180.75 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.57 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2863 mL	16.4317 mL	32.8634 mL	164.3169 mL
5 mM	0.6573 mL	3.2863 mL	6.5727 mL	32.8634 mL
10 mM	0.3286 mL	1.6432 mL	3.2863 mL	16.4317 mL
20 mM	0.1643 mL	0.8216 mL	1.6432 mL	8.2158 mL
50 mM	0.0657 mL	0.3286 mL	0.6573 mL	3.2863 mL
100 mM	0.0329 mL	0.1643 mL	0.3286 mL	1.6432 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

(-)-Oxypeucedanin hydrate

(-)-Oxypeucedanin hydrate

产品介绍

引用文献

计算器

体内实验配液计算器

剂量转换

关键词

(-)-Oxypeucedanin hydrate

(-)-Oxypeucedanin hydrate