Phenelzine sulfate

Name: Phenelzine sulfate
Brand: TargetMol
SKU: T12441
Price: 158 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.83%

货号 T12441Cas号 156-51-4

别名 硫酸苯乙肼, 苯肼,硫酸盐

Phenelzine sulfate 是一种非选择性的、不可逆的单胺氧化酶抑制剂 (MAOI)，可用作抗抑郁药和抗焦虑药。

Phenelzine sulfate

一键复制产品信息

很棒

纯度: 99.83%

货号 T12441 别名 硫酸苯乙肼, 苯肼,硫酸盐Cas号 156-51-4

Phenelzine sulfate 是一种非选择性的、不可逆的单胺氧化酶抑制剂 (MAOI)，可用作抗抑郁药和抗焦虑药。

规格	价格	库存
10 mg	¥ 158	现货
25 mg	¥ 242	现货
50 mg	¥ 343	现货
100 mg	¥ 496	现货
500 mg	¥ 1,360	现货
1 mL x 10 mM (in DMSO)	¥ 178	现货

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纯度: 99.83%

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COA HNMR LCMS 产品操作手册

产品介绍

Phenelzine sulfate AI Summary

Phenelzine sulfate exhibits a diverse range of bioactivities affecting various cellular processes, protein interactions, and viral mechanisms. It shows significant antiplasmodial activity against Plasmodium falciparum strains 7G8 and GB4, with IC50 values of 10000.0 nM and 15848.93 nM, respectively. The compound demonstrates multiple inhibitory effects, including on Lamin A splicing, JMJD2E, Tau fibril formation, ALDH1A1, Bloom's syndrome helicase (BLM), ROR gamma transcriptional activity, and Human tyrosyl-DNA phosphodiesterase 1 (TDP1). It also modulates miRNAs/activators of miR-21, PMP22 expression/activity, and induces ER stress response and DNA re-replication. Furthermore, Phenelzine sulfate blocks viral entry of various viruses like Marburg, Ebola, and Foot and Mouth Disease Virus and exhibits antiviral activity against SARS-CoV-2 by inhibiting the virus-induced cytotoxicity in Caco-2 and VERO-6 cells at a 10 uM concentration. However, it shows limited activity in inhibiting SARS-CoV-2 in Vero E6 cells with a low inhibition index of 0.04032. The compound can inhibit SARS-CoV-2 3CL-Pro protease by 32.83% at 20 µM. In cellular uptake mechanisms, Phenelzine sulfate significantly inhibits sodium fluorescein uptake in OATP1B1 and OATP1B3-transfected CHO cells, suggesting its interference in these pathways. Additionally, it displays a range of antifungal and antibacterial activities, with varying degrees of inhibition against Candida albicans, Cryptococcus neoformans, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, and MRSA..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Phenelzine sulfate is a non-selective and irreversible inhibitor of monoamine oxidase (MAOI), and with antidepressant and anxiolytic.
别名	硫酸苯乙肼, 苯肼,硫酸盐

化学信息

分子量	234.27
分子式	C₈H₁₄N₂O₄S
CAS No.	156-51-4
Smiles	OS(O)(=O)=O.NNCCc1ccccc1
密度	no data available

储存&溶解度

存储

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 250 mg/mL (1067.14 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (14.09 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2686 mL	21.3429 mL	42.6858 mL	213.4289 mL
5 mM	0.8537 mL	4.2686 mL	8.5372 mL	42.6858 mL
10 mM	0.4269 mL	2.1343 mL	4.2686 mL	21.3429 mL
20 mM	0.2134 mL	1.0671 mL	2.1343 mL	10.6714 mL
50 mM	0.0854 mL	0.4269 mL	0.8537 mL	4.2686 mL
100 mM	0.0427 mL	0.2134 mL	0.4269 mL	2.1343 mL