Palmitoylisopropylamide

Name: Palmitoylisopropylamide
Brand: TargetMol
SKU: T23119
Price: 303 CNY
Availability: InStock
Rating: 5 (10 reviews)

货号 T23119Cas号 189939-61-5 一键复制产品信息纯度: 99.93%

很棒

Palmitoylisopropylamide 是一种选择性 FAAH 抑制剂，抑制[H]-AEA摄取，在低浓度下抑制细胞增殖。

Palmitoylisopropylamide

一键复制产品信息

很棒

纯度: 99.93%

货号 T23119Cas号 189939-61-5

Palmitoylisopropylamide 是一种选择性 FAAH 抑制剂，抑制[H]-AEA摄取，在低浓度下抑制细胞增殖。

规格	价格	库存
1 mg	¥ 303	现货
5 mg	¥ 691	现货
10 mg	¥ 1,070	现货
25 mg	¥ 2,020	现货
50 mg	¥ 3,420	现货
100 mg	¥ 4,810	现货
200 mg	¥ 6,490	现货

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实验操作小课堂

常见问题解答

选择批次:

纯度: 99.93%

颜色: 白色

性状: Solid

资源下载: COA HNMR LCMS产品操作手册

产品介绍

Palmitoylisopropylamide AI Summary

Palmitoylisopropylamide exhibits bioactivities related to cannabinoid receptors and shows moderate inhibitory activity on the metabolism of N-arachidonoylethanolamine (AEA) in rat brain homogenates, with an IC50 value ranging from 12,882.5 nM to 14,125.38 nM. It demonstrates inhibition percentages ranging from 4.0% to 61.0% at various pH levels (6 and 9). Additionally, Palmitoylisopropylamide displays modest inhibitory effects on the specific binding of [3H]CP-55940 to human cannabinoid receptor 1 and [3H]WIN-55212-2 to human cannabinoid receptor 2 in Chinese hamster ovary cell membranes, with inhibition percentages of 25.4% and 12.3%, respectively. It also exhibits binding affinity against human Cannabinoid receptor 1 (CB1) and CB2 receptor and inhibits fatty acid amide hydrolase (FAAH) from rat brain homogenates at 10 uM and 100 uM concentrations. Moreover, it inhibits N-palmitoylethanolamine-selective acid amidase (NPAA) from rat lung homogenates at 100 uM. Palmitoylisopropylamide has an IC50 value of 13.0 nM for its potent inhibition of FAAH. Additionally, it exhibits bioactivities by inhibiting the Menin-MLL interaction in MLL-related leukemias, targeting the ERK signaling pathway, and inhibiting USP1/UAF1, with potencies of 35481.3 nM, 6309.6 nM, and 70794.6 nM, respectively..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.

化学信息

分子量	297.52
分子式	C₁₉H₃₉NO
CAS No.	189939-61-5
Smiles	C(CCCCCCCCCCCCC)CC(NC(C)C)=O
密度	0.853g/cm3

储存&溶解度

存储

Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: Soluble

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。