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AG311 is an inhibitor of complex I and hypoxia-induced HIF-1α stabilization. In vitro, AG311 induces rapid necrosis in numerous cancer cell lines. Within minutes, exposure to AG311 also results in mitochondrial depolarization, superoxide production, and increased intracellular calcium levels.
别名 AG-311, AG 311
AG311 is an inhibitor of complex I and hypoxia-induced HIF-1α stabilization. In vitro, AG311 induces rapid necrosis in numerous cancer cell lines. Within minutes, exposure to AG311 also results in mitochondrial depolarization, superoxide production, and increased intracellular calcium levels.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 11,700 | 6-8周 | |
| 50 mg | ¥ 15,300 | 6-8周 | |
| 100 mg | ¥ 19,500 | 6-8周 |
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| 产品描述 | AG311 is an inhibitor of complex I and hypoxia-induced HIF-1α stabilization. In vitro, AG311 induces rapid necrosis in numerous cancer cell lines. Within minutes, exposure to AG311 also results in mitochondrial depolarization, superoxide production, and increased intracellular calcium levels. |
| 别名 | AG-311, AG 311 |
| 分子量 | 321.4 |
| 分子式 | C17H15N5S |
| CAS No. | 1126602-42-3 |
| Smiles | S(C1=C2C=3C(NC2=CC=C1)=NC(N)=NC3N)C4=CC=C(C)C=C4 |
| 密度 | 1.46 g/cm3 (Predicted) |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
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