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Metolachlor
Synonyms: 异丙甲草胺货号 T19891Cas号 51218-45-2 一键复制产品信息纯度: 98.69%
很棒
很棒Metolachlor 是出苗前的选择性的，氯乙酰苯胺除草剂，由四种立体异构体组成的手性除草剂。它可用于控制玉米和其他农作物中的各种一年生草和阔叶杂草。
Metolachlor
一键复制产品信息 很棒纯度: 98.69%
货号 T19891Cas号 51218-45-2
别名 异丙甲草胺
Metolachlor 是出苗前的选择性的，氯乙酰苯胺除草剂，由四种立体异构体组成的手性除草剂。它可用于控制玉米和其他农作物中的各种一年生草和阔叶杂草。
其他形式的 “Metolachlor”:
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 148 | 现货 | |
| 1 mL x 10 mM (in DMSO) | ¥ 117 | 现货 |
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产品介绍
Metolachlor AI Summary
Metolachlor is a multifaceted bioactive molecule exhibiting a wide range of activities. It functions as:
- An antagonist of androgen receptor signaling with a potency of 19952.6 nM.
- An agonist of peroxisome proliferator-activated receptor delta signaling with a potency of 44668.4 nM.
- An antagonist of peroxisome proliferator-activated receptor gamma signaling with a potency of 44668.4 nM.
- An antagonist of peroxisome proliferator-activated receptor delta signaling with a potency of 39810.7 nM.
- An agonist of peroxisome proliferator-activated receptor gamma signaling with a potency of 39810.7 nM.
- An agonist of the antioxidant response element (ARE) signaling pathway, with potencies of 24336.5 nM and 38570.8 nM measured by Nrf2-dependent transcriptional activity.
- An inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1) with a potency of 29092.9 nM in the presence of CPT.
- An activator of the human pregnane X receptor (PXR) signaling pathway with a potency of 562.3 nM.
It also exhibits notable herbicidal properties:
- Inhibits desalted triosephosphate isomerase in Lolium multiflorum (Italian rye grass) shoots, with an activity of 9.57 nmol/sec per mg protein.
- Demonstrates strong pre- and post-emergence herbicidal activity against species such as Digitaria sanguinalis, Echinochloa crus-galli, Amaranthus retroflexus, Brassica rapa subsp. oleifera, and others, showing effective inhibition at specified concentrations.
- Exhibits selectivity, showing low toxicity against crop species like Zea mays var. SHEN DAN 17 and Brassica rapa subsp. oleifera var. JING GUAN 1.
Additionally, Metolachlor binds to the SafBP receptor in Zea mays seedlings with an IC50 value of 39810717.06 nM and potently inhibits sodium fluorescein uptake in OATP1B1 and OATP1B3-transfected CHO cells at a concentration of 10 µM, with inhibition percentages of 93.33% and 101.68%, respectively..
Note: Summary generated by AI. Data source: ChEMBL 
生物活性
化学信息
储存&溶解度
| 产品描述 | Metolachlor is an organic compound. Metolachlor is also widely used as an herbicide. |
| 别名 | 异丙甲草胺 |
| 分子量 | 283.79 |
| 分子式 | C15H22ClNO2 |
| CAS No. | 51218-45-2 |
| Smiles | CCc1cccc(C)c1N(C(C)COC)C(=O)CCl |
| 密度 | 1.1200 g/cm3 |
| 存储 | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 | |||||||||||||||||||||||||||||||||||
| 溶解度信息 | DMSO: 65 mg/mL (229.04 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。 | ||||||||||||||||||||||||||||||||||||
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
剂量转换
对于不同动物的给药剂量换算，您也可以参考 更多
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