Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 820 | 5日内发货 | ||
50 μg | ¥ 2,480 | 5日内发货 | ||
500 μg | ¥ 9,730 | 5日内发货 | ||
1 mg | ¥ 13,900 | 5日内发货 |
产品描述 | Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome. |
种属 | Human |
表达系统 | E. coli |
标签 | N-GST |
蛋白编号 | Q8IW75 |
别名 | Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, OL-64, SERPINA12, Serpin A12, Visceral Adipose-Specific Serpin |
氨基酸序列 | Leu21-Lys414 |
蛋白构建 | Leu21-Lys414 |
蛋白纯度 | Greater than 80% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 72 KDa (reducing condition) |
内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 160 mM NaCl, 0.2 mM PMSF, 1 mM DTT, 10% Glycerine, pH 7.2. |
存储 |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome. |
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Serpin A12 Protein, Human, Recombinant (GST) OL64 Visceral Adipose Tissue-Derived Serine Protease Inhibitor Vaspin SERPINA-12 OL 64 OL-64 SERPINA 12 SERPINA12 Serpin A12 Visceral Adipose-Specific Serpin recombinant recombinant-proteins proteins protein