还可以Globomycin, a lipopeptide antibiotic, is an inhibitor of signal peptidase II (LspA). It binds irreversibly to the peptidase, thereby inhibiting the processing of the prolipoprotein.
还可以Globomycin, a lipopeptide antibiotic, is an inhibitor of signal peptidase II (LspA). It binds irreversibly to the peptidase, thereby inhibiting the processing of the prolipoprotein.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 mg | 待询 | 期货 | |
| 500 mg | 待询 | 期货 |
| 产品描述 | Globomycin, a lipopeptide antibiotic, is an inhibitor of signal peptidase II (LspA). It binds irreversibly to the peptidase, thereby inhibiting the processing of the prolipoprotein. |
| 体外活性 | Globomycin effectively inhibits the growth of S. melliferum with MICs of 12.5 μM for strain B88 and 6.25 μM for strain BC3. It interferes with bacterial lipoprotein processing by inhibiting signal peptidase II in gracilicutes (Gram-negative eubacteria) and firmicutes (Gram-positive eubacteria) [1]. In B. diminuta DS010 cells treated with Globomycin, most organophosphate hydrolase (OPH) accumulates in the cytoplasm in an unprocessed form, whereas untreated cells show minimal precursor and increased mature OPH in the membrane fraction [2]. |
| 分子量 | 655.834 |
| 分子式 | C32H57N5O9 |
| CAS No. | 67076-74-8 |
| 密度 | 1.062 g/cm3 (Predicted) |
| 存储 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
嗨！有任何问题？点我咨询
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论内容