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CDK1/Cyc B-IN-1
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还可以产品编号 T61254Cas号 2459916-56-2
CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].
CDK1/Cyc B-IN-1
一键复制产品信息 还可以产品编号 T61254Cas号 2459916-56-2
CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 14,900 | 6-8周 | |
| 50 mg | ¥ 19,420 | 6-8周 | |
| 100 mg | ¥ 24,625 | 6-8周 |
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| 产品描述 | CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1]. |
| 靶点活性 | CDK1-CyclinB:97 nM |
| 体外活性 | CDK1/Cyc B-IN-1 (Compound 5) shows cytotoxic activity with IC 50 values of 5.33 ± 0.69 μM and 21.69 ± 1.04 μM against HCT-116 and WI-38, respectively [1]. |
| 分子量 | 353.85 |
| 分子式 | C14H12ClN3O2S2 |
| CAS No. | 2459916-56-2 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 一共给药动物 10 只 ，您使用的配方为 5% 
DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH2O， 那么您的工作液浓度为 2 mg/mL 。 剂量转换
对于不同动物的给药剂量换算，您也可以参考 更多
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