Name: Phenserine tartrate
Brand: TargetMol
SKU: T89337
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

10 mg

待询

10-14周

50 mg

待询

10-14周

生物活性

产品描述	Phenserine tartrate ((-)-Eseroline phenylcarbamate) is a derivative of Physostigmine and functions as an efficient, non-competitive, long-acting, and selective inhibitor of acetylcholinesterase (AChE). This compound reduces the formation of amyloid precursor protein (APP) and β-amyloid peptides (Aβ), potentially improving cognitive abilities and alleviating the progression of Alzheimers disease.
体外活性	Phenserine 在 CHO APP 751SW 细胞中的影响表明,使用 10 μM Phenserine 处理48小时后,细胞数量减少了 18.6%;而提高至 25 μM 时,APP 水平降低了 51.4%.
体内活性	Phenserine在剂量为1-4 mg/kg的范围内,通过腹膜内注射方式给予,连续四天处理雄性Fischer-344大鼠,可有效改善在空间记忆任务中由于胆碱能功能受损引起的学习障碍.
别名	(-)-Phenserine (+)-tartrate, (-)-Eseroline phenylcarbamate tartrate

化学信息

分子量	487.5
分子式	C₂₄H₂₉N₃O₈
CAS No.	156910-61-1
Smiles	[C@@H]([C@H](C(O)=O)O)(C(O)=O)O.C[C@]12C=3C(N(C)[C@]1(N(C)CC2)[H])=CC=C(OC(NC4=CC=CC=C4)=O)C3

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.

Phenserine tartrate