Glycylsarcosine

Name: Glycylsarcosine
Brand: TargetMol
SKU: T8915
Price: 119 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 98.47%

货号 T8915Cas号 29816-01-1

别名 甘氨酰肌氨酸, GLYCYL-SARCOSINE

Glycylsarcosine (GLYCYL-SARCOSINE) 是由甘氨酸的羧基与肌氨酸的氨基缩合而成的二肽

Glycylsarcosine

一键复制产品信息

很棒

纯度: 98.47%

货号 T8915 别名 甘氨酰肌氨酸, GLYCYL-SARCOSINECas号 29816-01-1

Glycylsarcosine (GLYCYL-SARCOSINE) 是由甘氨酸的羧基与肌氨酸的氨基缩合而成的二肽

规格	价格	库存	数量
200 mg	¥ 119	现货
500 mg	¥ 188	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 98.47%

联系我们获取更多批次信息

资源下载:

COA HPLC HNMR 产品操作手册

产品介绍

Glycylsarcosine AI Summary

Glycylsarcosine exhibits significant bioactivity related to its interactions with various transporter proteins, particularly PEPT1 and PEPT2. It acts as a substrate and modulator of these transporters, demonstrating different affinities across cell types and species. The compound shows complete absorption in the human intestine after oral administration, with varying permeabilities in different membrane models, including higher permeability in the 2/4/A1 cell model. It has a Ki value of 830,000 nM for the inhibition of the human intestinal peptide carrier and an EC50 value of 540,000 nM for activation of the human PEPT1 transporter, with a max activation of 101% relative to Gly-Sar. Additionally, the compound exhibits moderate to high permeability across human Caco-2 cells, evidenced by a Papp value of 1.1 x 10^-5 cm/s. Furthermore, it shows uptake and inhibition activities in PEPT1 and PEPT2-expressing cells with varying Km and Ki values, indicating its role in transporter-mediated drug absorption and potential implications in drug interactions..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Glycylsarcosine (GLYCYL-SARCOSINE) is a dipeptide obtained by formal condensation of the carboxy group of glycine with the amino group of sarcosine
别名	甘氨酰肌氨酸, GLYCYL-SARCOSINE

化学信息

分子量	146.14
分子式	C₅H₁₀N₂O₃
CAS No.	29816-01-1
Smiles	CN(CC(O)=O)C(=O)CN
密度	1.284g/cm3

储存&溶解度

存储	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	DMSO: Slightly soluble