Name: BAY-252
Brand: TargetMol
SKU: T78148
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 mg

待询

8-10周

50 mg

待询

8-10周

产品介绍

生物活性

产品描述	BAY-252 is a potent inhibitor of branched-chain amino acid transaminases 1 (BCAT1) and BCAT2, with IC50 of 2 μM for both enzymes. In addition to its inhibitory properties, BAY-252 serves as a chemical probe in cancer research, aiding in the investigation of metabolic pathways involving branched-chain amino acids.
体外活性	BAY-252在抑制MDA-MB-231细胞增殖方面表现出活性，其半抑制浓度(IC50)为2μM[1]。
别名	BAY252

化学信息

分子量	446.81
分子式	C₂₂H₁₄ClF₃N₂O₃
CAS No.	2639638-67-6
Smiles	O=C1C=C(NC(=O)N1C2=CC(OC=3C=CC=CC3C)=C(Cl)C=4C=CC=CC42)C(F)(F)F
颜色	White
物理性状	Solid

储存&溶解度

存储

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 100 mg/mL (223.81 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2381 mL	11.1904 mL	22.3809 mL	111.9044 mL
5 mM	0.4476 mL	2.2381 mL	4.4762 mL	22.3809 mL
10 mM	0.2238 mL	1.1190 mL	2.2381 mL	11.1904 mL
20 mM	0.1119 mL	0.5595 mL	1.1190 mL	5.5952 mL
50 mM	0.0448 mL	0.2238 mL	0.4476 mL	2.2381 mL
100 mM	0.0224 mL	0.1119 mL	0.2238 mL	1.1190 mL

体内实验配液计算器