DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 740 | 5日内发货 | ||
50 μg | ¥ 1,970 | 5日内发货 | ||
500 μg | ¥ 12,100 | 5日内发货 | ||
1 mg | ¥ 17,400 | 5日内发货 |
产品描述 | DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression. |
种属 | Human |
表达系统 | E. coli |
标签 | N-6xHis |
蛋白编号 | AAH07721.1 |
别名 | DNA Fragmentation Factor Subunit Alpha, DFF45, H13, ICAD, DFFA, DFF1, DNA Fragmentation Factor Subunit α, DNA Fragmentation Factor 45 kDa Subunit, DFF-45, Inhibitor of CAD |
氨基酸序列 | Met1-Thr331 |
蛋白构建 | Met1-Thr331 |
蛋白纯度 | Greater than 85% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 40-50 KDa (reducing condition) |
内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. |
存储 |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression. |
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DFF45 Protein, Human, Recombinant (His) DNA Fragmentation Factor Subunit Alpha DFF45 H 13 DFF-1 H-13 H13 DFF 1 ICAD DFFA DFF1 DFF 45 DNA Fragmentation Factor Subunit α DNA Fragmentation Factor 45 kDa Subunit DFF-45 Inhibitor of CAD recombinant recombinant-proteins proteins protein