Antimicrobial agent-21

Name: Antimicrobial agent-21
Brand: TargetMol
SKU: T67942
Price: 517 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.82%

货号 T67942Cas号 724746-07-0

Antimicrobial agent-21是一种有效的丝裂原活化蛋白激酶抑制剂，具有抗菌、抗炎和抗肿瘤活性，可用来治疗白内障，溃疡性结肠炎，脑膜炎和川崎氏病帕金森氏症。

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Antimicrobial agent-21

一键复制产品信息

很棒

纯度: 99.82%

货号 T67942Cas号 724746-07-0

规格	价格	库存
1 mg	¥ 517	现货
5 mg	¥ 1,300	现货
10 mg	¥ 1,880	现货
25 mg	¥ 2,900	现货
50 mg	¥ 3,920	现货
100 mg	¥ 5,290	现货
200 mg	¥ 6,900	现货
1 mL x 10 mM (in DMSO)	¥ 1,250	现货

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产品介绍

Antimicrobial agent-21 AI Summary

Antimicrobial agent-21 exhibits diverse bioactivities targeting various cellular pathways and disease mechanisms. It shows cytotoxicity towards Streptococcus with an EC50 of 23853.0 nM and is more potent against SK(-)GAS Group A Streptococcus with an EC50 of 1255.0 nM. The compound also demonstrates an ability to inhibit aggregate formation in a Huntington disease cell model at 1584.9 nM and enhances SMN2 splice variant expression with a potency of 5623.4 nM. Additionally, it inhibits multiple targets including ROR gamma transcriptional activity, Bacillus subtilis Sfp phosphopantetheinyl transferase, Mycobacterium tuberculosis H37Rv, and fructose-1,6-bisphosphate aldolase from Giardia Lamblia. Antimicrobial agent-21 also affects lipid storage, insulin promoter activity, TGF-b, Lassa Virus entry, and DNA re-replication in cancer cells, reflecting its broad-spectrum therapeutic potential..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Antimicrobial agent-21 is a potent mitogen activated protein kinase inhibitor with antibacterial, anti-inflammatory and antitumor activity for the treatment of cataracts, ulcerative colitis, meningitis and Kawasaki's disease and Parkinson's disease.

化学信息

分子量	319.38
分子式	C₁₈H₁₃N₃OS
CAS No.	724746-07-0
Smiles	O=C1C=2C(=C(C)SC2NC(=N1)C3=CC=CC=N3)C4=CC=CC=C4

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 10 mg/mL (31.31 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1311 mL	15.6553 mL	31.3107 mL	156.5533 mL
5 mM	0.6262 mL	3.1311 mL	6.2621 mL	31.3107 mL
10 mM	0.3131 mL	1.5655 mL	3.1311 mL	15.6553 mL
20 mM	0.1566 mL	0.7828 mL	1.5655 mL	7.8277 mL