Name: Zinc Protoporphyrin
Brand: TargetMol
SKU: T13396
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 395

5日内发货

5 mg

¥ 1,430

5日内发货

10 mg

¥ 2,160

In stock

25 mg

¥ 3,290

5日内发货

50 mg

¥ 4,700

5日内发货

1 mL x 10 mM (in DMSO)

¥ 1,990

In stock

产品介绍

生物活性

产品描述	Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-cancer activity.
体外活性	Zinc Protoporphyrin （Zn(II)-protoporphyrin IX；5μM；72小时）处理后，晚期凋亡和坏死细胞的比例从对照组的10.9%升至30.4% [3]。Zinc Protoporphyrin （1.25-40μM；48或72小时）对肿瘤细胞表现出细胞静止/细胞毒作用[3]。Zinc Protoporphyrin （2.5, 5μM；48或72小时）导致细胞G1期比例的剂量和时间依赖性减少[3]。Zinc Protoporphyrin （1.25-40μM；48小时）促进裂解（活化）caspase-3的积累[3]。
体内活性	Zinc Protoporphyrin 显示出剂量依赖的抗肿瘤效果，这通过肿瘤生长的延缓来表现[3]。
别名	锌原卟啉, ZnPP, Zn(II)-protoporphyrin IX, Zinc Protoporphyrin-9

化学信息

分子量	626.02
分子式	C₃₄H₃₂N₄O₄Zn
CAS No.	15442-64-5
Smiles	CC1=C(CCC(O)=O)C2=N\C\1=C/c1c(C=C)c(C)c3\C=C4/N=C(/C=c5/c(C)c(CCC(O)=O)\c(=C\2)n5[Zn]n13)C(C)=C4C=C
密度	no data available
颜色	Black
物理性状	Solid

储存&溶解度

存储

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (79.87 mM), Sonication is recommended.

H2O: < 0.1 mg/mL (insoluble)

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5974 mL	7.9870 mL	15.9739 mL	79.8697 mL
5 mM	0.3195 mL	1.5974 mL	3.1948 mL	15.9739 mL
10 mM	0.1597 mL	0.7987 mL	1.5974 mL	7.9870 mL
20 mM	0.0799 mL	0.3993 mL	0.7987 mL	3.9935 mL
50 mM	0.0319 mL	0.1597 mL	0.3195 mL	1.5974 mL

体内实验配液计算器