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顶部相关产品产品介绍化学信息储存和溶解信息计算器

ADMA-D6

货号 T70990Cas号 1313730-20-9 一键复制产品信息
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ADMA-D6 is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA (T7682) is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs)and degraded by dimethylarginine dimethylaminohydrolases (DDAHs)and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA (T7682)levels are increased concomitant with an increase in blood pressure in Dahl salt-sensitive rats fed a high-salt diet. ADMA (T7682)levels are increased in the plasma in a variety of endothelial dysfunction-related diseases,including hypertension,congestive heart failure,and end-stage renal disease.

ADMA-D6

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货号 T70990Cas号 1313730-20-9

ADMA-D6 is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA (T7682) is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs)and degraded by dimethylarginine dimethylaminohydrolases (DDAHs)and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA (T7682)levels are increased concomitant with an increase in blood pressure in Dahl salt-sensitive rats fed a high-salt diet. ADMA (T7682)levels are increased in the plasma in a variety of endothelial dysfunction-related diseases,including hypertension,congestive heart failure,and end-stage renal disease.

ADMA-D6
规格价格库存数量
1 mg
¥ 2,970
35日内发货
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产品介绍

生物活性
产品描述
ADMA-D6 is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA (T7682) is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA (T7682) levels are increased concomitant with an increase in blood pressure in Dahl salt-sensitive rats fed a high-salt diet. ADMA (T7682) levels are increased in the plasma in a variety of endothelial dysfunction-related diseases, including hypertension, congestive heart failure, and end-stage renal disease.
化学信息
分子量281.2106
分子式C8H14D6Cl2N4O2
CAS No.1313730-20-9
SmilesCl.Cl.[2H]C([2H])([2H])N(C(=N)NCCC[C@H](N)C(O)=O)C([2H])([2H])[2H]
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

30315-93-6
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