trans-Zeatin

Name: trans-Zeatin
Brand: TargetMol
SKU: TMS2181
Price: 170 CNY
Availability: InStock
Rating: 5 (10 reviews)

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纯度: 98.96%

货号 TMS2181Cas号 1637-39-4

别名 玉米素, 反-玉米素, (E)-Zeatin

trans-Zeatin ((E)-Zeatin) 是植物细胞分裂素，可抑制紫外线诱导的MEK/ERK 的活化，在细胞生长、分化和分裂中起着重要的作用。

trans-Zeatin

一键复制产品信息

很棒

纯度: 98.96%

货号 TMS2181 别名 玉米素, 反-玉米素, (E)-ZeatinCas号 1637-39-4

trans-Zeatin ((E)-Zeatin) 是植物细胞分裂素，可抑制紫外线诱导的MEK/ERK 的活化，在细胞生长、分化和分裂中起着重要的作用。

规格	价格	库存	数量
25 mg	¥ 190	现货
1 mL x 10 mM (in DMSO)	¥ 170	现货

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产品介绍

trans-Zeatin AI Summary

trans-Zeatin exhibits diverse bioactivities across several biological systems and assays. In plants, it demonstrates cytokinin-like effects, activating AHK3 and AHK4/CRE1 receptors in Arabidopsis thaliana to stimulate beta-galactosidase activity, promoting callus growth in tobacco, betacyanin synthesis in Amaranthus cotyledons, and chlorophyll retention in wheat, comparable to 6-benzylaminopurine. It inhibits RECQ1 DNA helicase with a potency of 2818.4 nM and APE1 with a potency of 1122.0 nM. It acts as an agonist of the Thyroid Stimulating Hormone Receptor, affecting intracelular cAMP concentrations in Parental HEK 293 cells (19952.6 nM). Additionally, it inhibits PTHR (11220.2 nM) and shows effects on Anthrax Lethal Toxin Internalization (12589.3 nM). trans-Zeatin has antiviral properties, inhibiting SARS-CoV-2 induced cytotoxicity in Caco-2 and VERO-6 cells at 10 µM concentration with varying inhibition levels, and shows SARS-CoV-2 3CL-Pro protease inhibition with activity percentages up to 19.53% at 20 µM. The compound also exhibits inhibitory activity against human HDAC6 enzyme with low percentages of inhibition in enzymatic assays..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
别名	玉米素, 反-玉米素, (E)-Zeatin

化学信息

分子量	219.24
分子式	C₁₀H₁₃N₅O
CAS No.	1637-39-4
Smiles	CC(CO)=CCNc1ncnc2[nH]cnc12
密度	1.40 g/cm3 (Predicted)
颜色	White
物理性状	Solid

储存&溶解度

存储

keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 35.71 mg/mL (162.88 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (4.56 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5612 mL	22.8061 mL	45.6121 mL	228.0606 mL
5 mM	0.9122 mL	4.5612 mL	9.1224 mL	45.6121 mL
10 mM	0.4561 mL	2.2806 mL	4.5612 mL	22.8061 mL
20 mM	0.2281 mL	1.1403 mL	2.2806 mL	11.4030 mL
50 mM	0.0912 mL	0.4561 mL	0.9122 mL	4.5612 mL
100 mM	0.0456 mL	0.2281 mL	0.4561 mL	2.2806 mL