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Lynestrenol

Name: Lynestrenol
Brand: TargetMol
SKU: T7974
Price: 109 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.94%

货号 T7974Cas号 52-76-6

别名 利奈孕醇

Lynestrenol 是孕烷 X 受体 (PXR) 激动剂，能够作用于 hPXR(EC50:41 µM) 和 zfPXR(EC50:0.23 µM)。它是合成的孕酮，具有免疫刺激作用。

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Lynestrenol

一键复制产品信息

很棒

纯度: 99.94%

货号 T7974 别名 利奈孕醇Cas号 52-76-6

Lynestrenol 是孕烷 X 受体 (PXR) 激动剂，能够作用于 hPXR(EC50:41 µM) 和 zfPXR(EC50:0.23 µM)。它是合成的孕酮，具有免疫刺激作用。

规格	价格	库存
1 mg	¥ 109	现货
5 mg	¥ 218	现货
10 mg	¥ 297	现货
25 mg	¥ 496	现货
50 mg	¥ 795	现货
100 mg	¥ 1,280	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

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纯度: 99.94%

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COA LCMS HNMR 产品操作手册

产品介绍

Lynestrenol AI Summary

Lynestrenol exhibits moderate acute and cholestatic liver toxicity but does not show severe liver-related bioactivities such as hepatitis, chronic liver disease, cirrhosis, or liver tumors. It binds differentially to progesterone receptors in various species, with moderate affinity in humans and sheep, higher affinity in rabbits, and lower affinity in guinea pigs. In antiviral studies, it shows limited efficacy against SARS-CoV-2, with an inhibition index of -0.1212 in Vero E6 cells and modest inhibition percentages in other assays. It also shows inhibition of human HDAC6 enzyme activity at low percentages. Lynestrenol interacts with multiple receptors and proteins, displaying varied bioactivities, including antagonist and agonist effects on receptors such as HRH2, ADRA1A, and CNR1. Additionally, it has been evaluated for enzyme inhibition, showing low activity against enzymes like PTGS2 and PDE4D..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist
别名	利奈孕醇

化学信息

分子量	284.44
分子式	C₂₀H₂₈O
CAS No.	52-76-6
Smiles	[H][C@]12CC[C@](O)(C#C)[C@]1(C)CC[C@@]1([H])[C@]3([H])CCCC=C3CC[C@]21[H]
密度	1.0083 g/cm3 (Estimated)
颜色	White
物理性状	Solid

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 56 mg/mL (196.88 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.03 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5157 mL	17.5784 mL	35.1568 mL	175.7840 mL
5 mM	0.7031 mL	3.5157 mL	7.0314 mL	35.1568 mL
10 mM	0.3516 mL	1.7578 mL	3.5157 mL	17.5784 mL
20 mM	0.1758 mL	0.8789 mL	1.7578 mL	8.7892 mL
50 mM	0.0703 mL	0.3516 mL	0.7031 mL	3.5157 mL
100 mM	0.0352 mL	0.1758 mL	0.3516 mL	1.7578 mL