Tie2 Inhibitor 7

Name: Tie2 Inhibitor 7
Brand: TargetMol
SKU: T36718
Rating: 4.5 (1 reviews)

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产品编号 T36718Cas号 1020412-97-8

Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.

Tie2 Inhibitor 7

还可以

产品编号 T36718Cas号 1020412-97-8

规格	价格	库存	数量
1 mg	待估	35日内发货
5 mg	待估	35日内发货

大包装 & 定制

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产品介绍

生物活性

产品描述	Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.
靶点活性	Tie2:1 μM, Tie2:1.3 μM

化学信息

分子量	529.63
分子式	C₃₁H₃₅N₃O₅
CAS No.	1020412-97-8

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	DMF: 14 mg/mL (26.43 mM), Sonication is recommended. Ethanol: 1 mg/mL (1.89 mM), Sonication is recommended. DMSO: 20 mg/mL (37.76 mM), Sonication is recommended. DMSO:PBS (pH 7.2)(1:9): 0.1 mg/mL (0.19 mM), Sonication is recommended.