规格

价格

库存

数量

1 mg

¥ 987

现货

5 mg

¥ 3,290

现货

10 mg

¥ 4,730

现货

25 mg

¥ 7,260

现货

50 mg

¥ 9,790

现货

100 mg

¥ 13,200

现货

200 mg

¥ 17,800

现货

生物活性

产品描述	AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2.AMP-Deoxynojirimycin is a potent inhibitor of GlcCer biosynthesis and is used in the study of Parkinson's and diabetes.
体外活性	In 3T3-L1 cells, AMP-Deoxynojirimycin (10 μM) significantly inhibits the leucine and C17ISO-induced phosphorylation of P70S6K[2].
别名	AMP-DNM

化学信息

分子量	397.55
分子式	C₂₂H₃₉NO₅
CAS No.	216758-20-2
Smiles	C(OCCCCCN1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1)C23CC4CC(C2)CC(C3)C4
颜色	White
物理性状	Solid

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 40 mg/mL (100.62 mM), Sonication is recommended.

DMF: 50 mg/mL (125.77 mM), Sonication is recommended.

Ethanol: 20 mg/mL (50.31 mM), Sonication is recommended.

Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL (1.26 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (5.03 mM), Sonication is recommeded.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

Ethanol/DMSO/DMF