Sulfaquinoxaline

Name: Sulfaquinoxaline
Brand: TargetMol
SKU: T1177
Price: 137 CNY
Availability: InStock
Rating: 5 (10 reviews)

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纯度: 99.81%

货号 T1177Cas号 59-40-5

别名 磺胺喹恶啉, 磺胺喹噁啉, Sulphaquinoxaline, Sulfabenzpyrazine, Avicocid

Sulfaquinoxaline (Sulfabenzpyrazine) 是一种兽用抗菌剂，对革兰氏阴性菌和革兰氏阳性菌均有活性。它能用于预防球虫病和细菌感染。

Sulfaquinoxaline

一键复制产品信息

很棒

纯度: 99.81%

货号 T1177 别名 磺胺喹恶啉, 磺胺喹噁啉, Sulphaquinoxaline, Sulfabenzpyrazine, AvicocidCas号 59-40-5

Sulfaquinoxaline (Sulfabenzpyrazine) 是一种兽用抗菌剂，对革兰氏阴性菌和革兰氏阳性菌均有活性。它能用于预防球虫病和细菌感染。

规格	价格	库存
100 mg	¥ 137	现货
500 mg	¥ 289	现货
1 mL x 10 mM (in DMSO)	¥ 148	现货

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COA HNMR LCMS 产品操作手册

产品介绍

Sulfaquinoxaline AI Summary

Sulfaquinoxaline exhibits a diverse range of bioactivities across various assays. It demonstrates potent inhibition of Lamin A splicing with a potency of 56.2 nM and shows inhibitory effects on Cytochrome P450 2C9 with a potency of 3981.1 nM, confirmed by an AC50 value of 3981.07 nM in the Cytochrome panel assay. In NCI human tumor cell line growth inhibition assays, the compound's GI50 values vary significantly from 10.0 nM to 100,000.0 nM across different cell lines. Additionally, it shows activity in assays for the Agonist of gsp mutation, Integrin-Mediated Alleviation for Muscular Dystrophy, and PTHR Inhibitors. In antiviral screening, Sulfaquinoxaline blocks the entry of Ebola Virus across channels with AC50 values ranging from 1.778 µM to 35481.3 nM and shows activity against SARS-CoV-2, with an IC50 value greater than 20,000.0 nM in VERO-6 cells. However, it lacks significant antibacterial and antifungal activities, with MIC values exceeding 10,000.0 nM and does not exhibit cytotoxicity against HEK293 cells, having a CC50 value also above 10,000.0 nM. Additionally, it acts as an inhibitor in an HDAC6 enzymatic assay, showing -38.71% inhibition with a commercial peptide substrate..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent.
别名	磺胺喹恶啉, 磺胺喹噁啉, Sulphaquinoxaline, Sulfabenzpyrazine, Avicocid

化学信息

分子量	300.34
分子式	C₁₄H₁₂N₄O₂S
CAS No.	59-40-5
Smiles	NC1=CC=C(C=C1)S(=O)(=O)NC1=NC2=CC=CC=C2N=C1
密度	1.3196 g/cm3 (Estimated)
颜色	Yellow
物理性状	Solid

储存&溶解度

存储

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 7.5 mg/L, Sonication is recommended.

DMSO: 250 mg/mL (832.39 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (16.65 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3296 mL	16.6478 mL	33.2956 mL	166.4780 mL
5 mM	0.6659 mL	3.3296 mL	6.6591 mL	33.2956 mL
10 mM	0.3330 mL	1.6648 mL	3.3296 mL	16.6478 mL
20 mM	0.1665 mL	0.8324 mL	1.6648 mL	8.3239 mL
50 mM	0.0666 mL	0.3330 mL	0.6659 mL	3.3296 mL
100 mM	0.0333 mL	0.1665 mL	0.3330 mL	1.6648 mL