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N-Acetyl-L-phenylalanine

Name: N-Acetyl-L-phenylalanine
Brand: TargetMol
SKU: T4781
Price: 137 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.74%

货号 T4781Cas号 2018-61-3

别名 N-乙酰-L-苯丙氨酸, N-Ac-Phenylalanine

N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) 是一种大肠杆菌中的主要酰基氨基酸，由 L-苯丙氨酸和乙酰辅酶 A 合成。

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N-Acetyl-L-phenylalanine

一键复制产品信息

很棒

纯度: 99.74%

货号 T4781 别名 N-乙酰-L-苯丙氨酸, N-Ac-PhenylalanineCas号 2018-61-3

N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) 是一种大肠杆菌中的主要酰基氨基酸，由 L-苯丙氨酸和乙酰辅酶 A 合成。

规格	价格	库存
10 mg	¥ 137	现货
25 mg	¥ 198	现货
50 mg	¥ 289	现货
100 mg	¥ 413	现货
500 mg	¥ 828	现货
1 g	¥ 1,230	现货
1 mL x 10 mM (in DMSO)	¥ 195	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.74%

颜色: 白色

性状: Solid

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资源下载:

COA LCMS HNMR 产品操作手册

产品介绍

N-Acetyl-L-phenylalanine AI Summary

N-Acetyl-L-phenylalanine inhibits the uptake of L-tryptophan in Xenopus laevis oocytes, showing varying degrees of inhibition (from 90% to 100%), indicating potential bioactivity related to tryptophan transport processes. The compound also exhibits antiviral activity against SARS-CoV-2, inhibiting the cytotoxicity in Caco-2 and VERO-6 cells at a concentration of 10 µM, showing inhibition rates of 20.55% and 0.1% respectively after 48 hours. Additionally, N-Acetyl-L-phenylalanine has demonstrated 13.69% inhibition of the SARS-CoV-2 3CL-Pro protease at 20 µM, suggesting its role in interfering with the virus's replication process. Furthermore, it shows inhibitory activity towards the human HDAC6 enzyme with 4.6% inhibition using a commercial peptide substrate and -7.32% inhibition using a custom peptide substrate, indicating its potential as an HDAC6 inhibitor..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述

N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) is an essential amino acid produced for medical, feed, and nutritional applications. It appears in large amount in urine of patients with phenylketonuria which is a human genetic disorder due to the lack of phenylalanine hydroxylase, the enzyme necessary to metabolize phenylalanine to tyrosine. Acetylphenylalanine is a product of enzyme phenylalanine N-acetyltransferase in the pathway phenylalanine metabolism.

别名

N-乙酰-L-苯丙氨酸, N-Ac-Phenylalanine

化学信息

分子量	207.23
分子式	C₁₁H₁₃NO₃
CAS No.	2018-61-3
Smiles	[H][C@](Cc1ccccc1)(NC(C)=O)C(O)=O
密度	1.1878 g/cm3 (Estimated)

储存&溶解度

存储

溶解度信息

DMSO: 250 mg/mL (1206.39 mM), Sonication is recommended.

Ethanol: 20 mg/mL (96.51 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.65 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8256 mL	24.1278 mL	48.2556 mL	241.2778 mL
5 mM	0.9651 mL	4.8256 mL	9.6511 mL	48.2556 mL
10 mM	0.4826 mL	2.4128 mL	4.8256 mL	24.1278 mL
20 mM	0.2413 mL	1.2064 mL	2.4128 mL	12.0639 mL
50 mM	0.0965 mL	0.4826 mL	0.9651 mL	4.8256 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0483 mL	0.2413 mL	0.4826 mL	2.4128 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。