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2-(Phosphonooxy)benzoic acid

Name: 2-(Phosphonooxy)benzoic acid
Brand: TargetMol
SKU: T1427
Price: 189 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: 磷柳酸, Salicyl phosphate, Fosfosal, Disdolen, 2-phosphonoxy benzoic acid

货号 T1427Cas号 6064-83-1 一键复制产品信息纯度: 97.19%

很棒

2-(Phosphonooxy)benzoic acid (Fosfosal) 是一种非乙酰化的水杨酸衍生物，对炎性疾病以及止痛具有潜在的研究价值。

2-(Phosphonooxy)benzoic acid

一键复制产品信息

很棒

纯度: 97.19%

货号 T1427Cas号 6064-83-1

别名 磷柳酸, Salicyl phosphate, Fosfosal, Disdolen, 2-phosphonoxy benzoic acid

2-(Phosphonooxy)benzoic acid (Fosfosal) 是一种非乙酰化的水杨酸衍生物，对炎性疾病以及止痛具有潜在的研究价值。

规格	价格	库存
1 mg	¥ 189	现货
5 mg	¥ 428	现货
10 mg	¥ 728	现货
25 mg	¥ 1,530	现货
50 mg	¥ 2,390	现货
100 mg	¥ 3,590	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

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纯度: 97.19%

颜色: 白色

性状: Solid

资源下载: COA LCMS HNMR产品操作手册

产品介绍

2-(Phosphonooxy)benzoic acid AI Summary

2-(Phosphonooxy)benzoic acid exhibits diverse bioactivities and antiviral properties. It shows significant binding affinity towards the phosphotyrosine binding pocket of the Src protein tyrosine kinase SH2 domain with an IC50 value of 2,000,000.0 nM. The compound demonstrates inhibitory activity against a range of targets including HSD17B4, JMJD2E, ALDH1A1, Ubiquitin-specific Protease USP2a, HPGD, and the malarial parasite plastid, with potency values between 3981.1 nM and 4256.2 nM. It has also shown potential in blocking Ebola Virus entry with AC50 values from 1.995 µM to 8.913 µM, and moderate activity in cell viability assays with an IC50 of 20,000.0 nM across various cell lines. Furthermore, 2-(Phosphonooxy)benzoic acid demonstrates inhibition of sodium fluorescein uptake in OATP1B1 and OATP1B3-transfected CHO cells, suggesting activity against these transporters. It also exhibits low-level inhibition of SARS-CoV-2 replication in Vero E6 cells and antiviral activity in HRCE cells against the USA-WA1/2020 strain, with a hit score of 0.1484. However, its antiviral IC50 values exceed 20,000.0 nM in different assays, indicating limited potency. Additionally, the compound shows toxicity in rats with a pLD50 of 7.01, and has no significant bioactivity in various in vitro receptor and enzyme assays, with AC50 values greater than 30,000.0 nM, suggesting weak binding affinity. Overall, 2-(Phosphonooxy)benzoic acid has multifaceted bioactivities and potential as a multifunctional compound in various biological contexts..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	2-(Phosphonooxy)benzoic acid (Fosfosal), used as the anti-inflammatory agent, has the anti-bacterial effect.
别名	磷柳酸, Salicyl phosphate, Fosfosal, Disdolen, 2-phosphonoxy benzoic acid

化学信息

分子量	218.1
分子式	C₇H₇O₆P
CAS No.	6064-83-1
Smiles	OC(=O)c1ccccc1OP(O)(O)=O
密度	1.695 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 60 mg/mL (275.1 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5851 mL	22.9253 mL	45.8505 mL	229.2526 mL
5 mM	0.9170 mL	4.5851 mL	9.1701 mL	45.8505 mL
10 mM	0.4585 mL	2.2925 mL	4.5851 mL	22.9253 mL
20 mM	0.2293 mL	1.1463 mL	2.2925 mL	11.4626 mL
50 mM	0.0917 mL	0.4585 mL	0.9170 mL	4.5851 mL
100 mM	0.0459 mL	0.2293 mL	0.4585 mL	2.2925 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。