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Carbaryl

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纯度: 99.75%

货号 T0790Cas号 63-25-2

别名 甲萘威, Sevin, 1-naphthyl methylcarbamate

Carbaryl (1-naphthyl methylcarbamate) 可作为一种杀虫剂。

Carbaryl
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Carbaryl

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Rating icon 很棒

纯度: 99.75%

货号 T0790 别名 甲萘威, Sevin, 1-naphthyl methylcarbamateCas号 63-25-2

Carbaryl (1-naphthyl methylcarbamate) 可作为一种杀虫剂。

规格价格库存数量
2 mg
¥ 112
现货
5 mg
¥ 162
现货
10 mg
¥ 223
现货
25 mg
¥ 355
现货
50 mg
¥ 569
现货
100 mg
¥ 892
现货
200 mg
¥ 1,330
现货
500 mg
¥ 2,270
现货
1 mL x 10 mM (in DMSO)
¥ 189
现货
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产品介绍


Carbaryl AI Summary
Carbaryl exhibits diverse bioactivities across several biochemical pathways and cellular processes. It is a potent inhibitor of multiple forms of acetylcholinesterase (AChE) from various sources including bovine erythrocytes, eel, and insects, with IC50 values ranging from 29.0 nM to 57400.0 nM. The compound also shows insecticidal activity against several pests such as southern Corn rootworm, Anopheles gambiae mosquitoes, Nephotettix cincticeps, Musca domestica, Dendroctonus ponderosae, and Drosophila suzukii, with LD50 values highlighting its potent efficacy. Its highest insecticidal activity is noted in assays with potent low LC50 values. Additionally, Carbaryl exhibits bioactivity as an inhibitor of fatty acid amide hydrolase (FAAH) in rat brain membranes and human FAAH with IC50 values greater than 30000.0 nM. It shows notable inhibition of SARS-CoV-2 3CL-Pro protease and displays antiviral activity against SARS-CoV-2-induced cytotoxicity in Caco-2 and VERO-6 cells at varied concentrations. Carbaryl also disrupts mitochondrial membrane potential, has selectivity towards AChE in Anopheles gambiae compared to human AChE, and shows an array of effects on signaling pathways, including GCN5L2, ERK, p53, and several others. Furthermore, it demonstrates high genotoxic activity in soybean, contact toxicity towards Trichogramma nubilale, and significant effects on Daphnia magna and Cheumatopsyche brevilineata larvae. Overall, Carbaryl is a multifunctional compound with significant biochemical and physiological effects, notably as an insecticide and antiviral agent..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly low toxicity from dermal absorption and is used for control of head lice in some countries.
别名甲萘威, Sevin, 1-naphthyl methylcarbamate
化学信息
分子量201.22
分子式C12H11NO2
CAS No.63-25-2
SmilesCNC(=O)OC1=CC=CC2=CC=CC=C12
密度1.183 g/cm3
颜色White
物理性状solid
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
DMSO: 50 mg/mL (248.48 mM), Sonication is recommended.
体内实验配方
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.94 mM), Sonication is recommended.
请按顺序添加溶剂,在添加下一种溶剂之前,尽可能使溶液澄清。如有必要,可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考,体内配方并不是绝对的,请根据不同情况进行调整。
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM4.9697 mL24.8484 mL49.6968 mL248.4842 mL
5 mM0.9939 mL4.9697 mL9.9394 mL49.6968 mL
10 mM0.4970 mL2.4848 mL4.9697 mL24.8484 mL
20 mM0.2485 mL1.2424 mL2.4848 mL12.4242 mL
50 mM0.0994 mL0.4970 mL0.9939 mL4.9697 mL
100 mM0.0497 mL0.2485 mL0.4970 mL2.4848 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
TargetMol | Animal experiments 比如您的给药剂量是10 mg/kg,每只动物体重20g,给药体积100 μLTargetMol | Animal experiments 一共给药动物10只,您使用的配方为5%TargetMol | reagent DMSO + 30%PEG300 + 5%Tween 80 + 60%Saline/PBS/ddH2O, 那么您的工作液浓度为2mg/mL
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent ( 母液浓度为 40 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:50μLDMSOTargetMol | reagent 母液,添加 300 μLPEG300TargetMol | reagent 混匀澄清,再加 50μLTween80, 混匀澄清,再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如: DMSOPEG300 / PEG400Tween 80SBE-β-CD玉米油 等, 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

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