L-Alanine

Name: L-Alanine
Brand: TargetMol
SKU: TJO2729
Price: 333 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.83%

货号 TJO2729Cas号 56-41-7

别名 丙氨酸, L-2-Aminopropionic acid, alanine

L-Alanine (L-2-Aminopropionic acid) 是一种非必需氨基酸，可参与糖和酸的代谢，为肌肉组织、大脑和中枢神经系统提供能量，并增强免疫力。

L-Alanine

一键复制产品信息

很棒

纯度: 99.83%

货号 TJO2729 别名 丙氨酸, L-2-Aminopropionic acid, alanineCas号 56-41-7

L-Alanine (L-2-Aminopropionic acid) 是一种非必需氨基酸，可参与糖和酸的代谢，为肌肉组织、大脑和中枢神经系统提供能量，并增强免疫力。

规格	价格	库存	数量
500 mg	¥ 333	现货
5 g	¥ 418	5日内发货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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COA LCMS HNMR 产品操作手册

产品介绍

L-Alanine AI Summary

L-Alanine has been tested for various biological activities across different assays. It activates carbonic anhydrase isozymes with KA values of 54.0 µM (hCA I), 150.0 µM (hCA II), and 66.0 µM (bCA IV). It shows bioactivity on Alanine racemase from *Pseudomonas aeruginosa* with a Km value of 14.2 mM, and inhibits the N-methyl-D-aspartate glutamate receptor 1 in rats with IC50 values of 78.0 µM and 198.0 µM for different conditions. Additionally, it inhibits human Tyrosyl-DNA Phosphodiesterase (TDP1) and Human Apurinic/apyrimidinic Endonuclease 1 (APE1) with potencies of 2.5 µM and 354.8 nM respectively. It also inhibits human PAT1-mediated L-[3H]proline uptake in Caco2 cells with a Ki value of 2.8 mM. The compound promotes insulin release in rat BRIN-BD11 cells at 10 mM concentration, and inhibits ASCT2 mediated [3H]-D-serine uptake in rat hippocampal astrocytes by 25% at 1 mM concentration. It shows antiviral activity against SARS-CoV-2 in both Caco-2 and VERO-6 cells, with marginal inhibition rates. Additionally, it displays inhibitory activity against SARS-CoV-2 3CL-Pro protease and less than 50% inhibition in binding assays for FIBCD1 and acetylated BSA. L-Alanine also exhibits substrate activity at *Escherichia coli* B alanine racemase (Vmax of 6360 /min, Km of 1.3 mM) and HDAC6 inhibition varying from -21.28% to -3.75% depending on the peptide substrate. Despite this, it shows limited overall bioactivity as the AC50 values in all assays exceed 30.0 µM, suggesting minimal impact on the tested biological pathways..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	L-Alanine (L-2-Aminopropionic acid) is an Amino Acid. The chemical classification of alanine is Amino Acids. Alanine is a small non-essential amino acid in humans, Alanine is one of the most widely used for protein construction and is involved in the metabolism of tryptophan and vitamin pyridoxine.
别名	丙氨酸, L-2-Aminopropionic acid, alanine

化学信息

分子量	89.09
分子式	C₃H₇NO₂
CAS No.	56-41-7
Smiles	[C@@H](C(O)=O)(C)N
密度	1.432 g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: < 1 mg/mL (insoluble or slightly soluble)

H2O: 71.43 mg/mL (801.77 mM), Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	11.2246 mL	56.1230 mL	112.2460 mL	561.2302 mL
5 mM	2.2449 mL	11.2246 mL	22.4492 mL	112.2460 mL
10 mM	1.1225 mL	5.6123 mL	11.2246 mL	56.1230 mL
20 mM	0.5612 mL	2.8062 mL	5.6123 mL	28.0615 mL
50 mM	0.2245 mL	1.1225 mL	2.2449 mL	11.2246 mL
100 mM	0.1122 mL	0.5612 mL	1.1225 mL	5.6123 mL