DNMDP

Name: DNMDP
Brand: TargetMol
SKU: T15147
Rating: 4.5 (1 reviews)

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产品编号 T15147Cas号 328104-79-6

DNMDP is a phosphodiesterase 3A inhibitor with clear cell-selective cytotoxicity. DNMDP binding to PDE3A promotes interaction between PDE3A and Schlafen 12.

DNMDP

还可以

产品编号 T15147Cas号 328104-79-6

DNMDP is a phosphodiesterase 3A inhibitor with clear cell-selective cytotoxicity. DNMDP binding to PDE3A promotes interaction between PDE3A and Schlafen 12.

规格	价格	库存
2 mg	¥ 819	5日内发货
25 mg	¥ 5,380	6-8周
50 mg	¥ 6,990	6-8周
100 mg	¥ 10,800	6-8周

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产品描述	DNMDP is a phosphodiesterase 3A inhibitor with clear cell-selective cytotoxicity. DNMDP binding to PDE3A promotes interaction between PDE3A and Schlafen 12.
体外活性	DNMDP (0-1000 μM; 48 hours) displays clear cell-selective cytotoxicity. HeLa cells undergo apoptosis upon DNMDP treatment, indicates by caspase activity detected by a caspase-sensitive luciferase assay and by PARP cleavage. DNMDP (100 nM) specifically inhibits both PDE3A and PDE3B, but it weakly inhibits PDE10. It also had little or no detectable effect on other phosphodiesterases.