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Carbendazim
Synonyms: 多菌灵, Mercarzole, Carbendazole, Bavistin货号 T3124Cas号 10605-21-7 一键复制产品信息纯度: 99.82%
很棒
很棒Carbendazim (Mercarzole) 是一种具有抗肿瘤活性的苯并咪唑衍生物，可用于癌症研究。它是一种口服广谱苯并咪唑杀菌剂，可作为真菌疾病研究的杀虫剂。
Carbendazim
一键复制产品信息 很棒纯度: 99.82%
货号 T3124Cas号 10605-21-7
别名 多菌灵, Mercarzole, Carbendazole, Bavistin
Carbendazim (Mercarzole) 是一种具有抗肿瘤活性的苯并咪唑衍生物，可用于癌症研究。它是一种口服广谱苯并咪唑杀菌剂，可作为真菌疾病研究的杀虫剂。
其他形式的 “Carbendazim”:
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 mg | ¥ 298 | 现货 | |
| 100 mg | ¥ 418 | 现货 | |
| 500 mg | ¥ 587 | 现货 | |
| 1 g | ¥ 756 | 现货 | |
| 5 g | ¥ 2,277 | 现货 |
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍
Carbendazim AI Summary
Carbendazim is a versatile bioactive agent with a multitude of biological activities. It shows strong antifungal activity against a wide range of fungi, including Rhizoctonia solani, Fusarium oxysporum, and Aspergillus niger, with MIC values as low as 6.25 µg/mL. The compound demonstrates potent inhibition of mycelial growth and spore germination, suggesting its potential as a broad-spectrum antifungal agent. Additionally, Carbendazim has antiparasitic activity against Giardia lamblia with an IC50 of 57.0 nM, and it inhibits tubulin polymerization in both Giardia lamblia and Entamoeba histolytica.
It also acts as an inhibitor of Co2+-loaded Methionine aminopeptidase (MetAP) expressed in Escherichia coli, though with varying degrees of potency, showing an inhibition percentage of 34.0% at a 25 µM concentration. Aside from its antifungal and antiparasitic properties, the compound has demonstrated antiviral activity against SARS-CoV-2, although not strong enough to be considered a major hit.
Moreover, Carbendazim has been assessed for cytotoxicity, showing activity against various human tumor cell lines and causing significant reductions in cell viability through different mechanisms. It shows potential for application in agricultural, pharmaceutical, and therapeutic fields due to its effective bioactive properties against a range of pathogens and cells..
Note: Summary generated by AI. Data source: ChEMBL 
生物活性
化学信息
储存&溶解度
| 产品描述 | Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspecified site on tubulin and suppresses microtubule assembly dynamic. This results in cell cycle arrest at the G2/M phase and an induction of apoptosis. |
| 别名 | 多菌灵, Mercarzole, Carbendazole, Bavistin |
| 分子量 | 191.19 |
| 分子式 | C9H9N3O2 |
| CAS No. | 10605-21-7 |
| Smiles | O=C(OC)NC1=NC=2C=CC=CC2N1 |
| 密度 | 1.4500 g/cm3 |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 | |||||||||||||||||||||||||
| 溶解度信息 | DMSO: 7.82 mg/mL (40.9 mM)  | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
DMSO
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。 | ||||||||||||||||||||||||||
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
剂量转换
对于不同动物的给药剂量换算，您也可以参考 更多
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