hMAO-B-IN-32

Name: hMAO-B-IN-32
Brand: TargetMol
SKU: T78232
Price: 121 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.97%

货号 T78232Cas号 28705-46-6

别名 Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate

hMAO-B-IN-32 是一种具有有效性和选择性的 hMAO-B 抑制剂(IC50：45.52 μM)。

hMAO-B-IN-32

一键复制产品信息

很棒

纯度: 99.97%

货号 T78232 别名 Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylateCas号 28705-46-6

hMAO-B-IN-32 是一种具有有效性和选择性的 hMAO-B 抑制剂(IC50：45.52 μM)。

规格	价格	库存	数量
500 mg	¥ 121	现货
1 g	¥ 195	现货

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产品介绍

hMAO-B-IN-32 AI Summary

hMAO-B-IN-32 shows no significant cytotoxicity against human OVCAR5 and LOXIMVI cells after 96 hours, with IC50 values above 10000.0 nM. It exhibits a minimal effect on calf thymus DNA binding affinity, indicated by a small change in thermal denaturation temperature (ΔTm = 0.2 degrees Celsius) at a concentration of 20 µM over different time points (4, 18, and 72 hours). Additionally, hMAO-B-IN-32 inhibits human recombinant monoamine oxidase-B (MAO-B) with an IC50 value of 45520.0 nM and has a selectivity ratio of the IC50 for human recombinant MAO-A to IC50 for human recombinant MAO-B greater than 2.2..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.
别名	Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate

化学信息

分子量	289.33
分子式	C₁₆H₁₉NO₄
CAS No.	28705-46-6
Smiles	CCOC(=O)c1cc2ccc(cc2oc1=O)N(CC)CC

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (172.81 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4563 mL	17.2813 mL	34.5626 mL	172.8131 mL
5 mM	0.6913 mL	3.4563 mL	6.9125 mL	34.5626 mL
10 mM	0.3456 mL	1.7281 mL	3.4563 mL	17.2813 mL
20 mM	0.1728 mL	0.8641 mL	1.7281 mL	8.6407 mL
50 mM	0.0691 mL	0.3456 mL	0.6913 mL	3.4563 mL
100 mM	0.0346 mL	0.1728 mL	0.3456 mL	1.7281 mL