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Stevioside

Name: Stevioside
Brand: TargetMol
SKU: T2911
Price: 108 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.89%

货号 T2911Cas号 57817-89-7

别名 甜菊苷, 蛇菊苷

Stevioside 是一种天然甜味剂，从甜叶菊叶中提取的获得，具有抗癌作用。

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Stevioside

一键复制产品信息

很棒

纯度: 99.89%

货号 T2911 别名 甜菊苷, 蛇菊苷Cas号 57817-89-7

Stevioside 是一种天然甜味剂，从甜叶菊叶中提取的获得，具有抗癌作用。

规格	价格	库存
5 mg	¥ 108	现货
10 mg	¥ 143	现货
25 mg	¥ 259	现货
50 mg	¥ 376	现货
100 mg	¥ 548	现货
500 mg	¥ 1,330	现货
1 g	¥ 1,960	现货
1 mL x 10 mM (in DMSO)	¥ 158	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

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纯度: 99.89%

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COA HNMR LCMS 产品操作手册

产品介绍

Stevioside AI Summary

Stevioside exhibits multiple bioactivities, including inhibition of HIV1 reverse transcriptase (IC50 >200.0 µg/mL) and cytotoxicity against human Raji cells (cell viability 60.0%). The compound shows potent inhibition of TPA-induced EBV-early antigen activation in human Raji cells, with activities ranging from 100.0% at a 10 molar ratio to 12.5% at a 1000 molar ratio. It also demonstrates antioxidant activity with a hydroxyl radical scavenging IC50 value of 1500000.0 nM, and agonist activity at the glucocorticoid receptor in mouse RAW264.7 cells, with a firefly/renilla luciferase ratio of 1.96 at 10 µM concentration. In sensory evaluations, Stevioside displays sweet taste properties at 500 p.p.m., with a sweetness intensity relative to 10% sucrose (Ip = 0.9), high potency by weight (Pw = 190.0), and molar basis (Pm = 440.0). The sensory scores are 62.0 for sweetness, 30.0 for bitterness, and 8.0 for other properties. In animal models, Stevioside shows varied bioactivities related to renal excretion in Wistar rats, influencing renal clearance and excretion mechanisms depending on dosage. It also induces insulin sensitivity in Syrian golden hamsters, increasing glucose uptake 2.1-fold under normal conditions and 4.4-fold under insulin-resistant conditions, while downregulating glucose uptake in the jejunum by 43.0% at 1 mM after 60 minutes. Additionally, the compound inhibits DMBA-induced/TPA-promoted and peroxynitrite-induced/TPA-promoted carcinogenesis in Sencar mice, reducing the number of skin papillomas per mouse and showing reductions after a 20-week treatment duration. In terms of toxicity, Stevioside displays acute toxicity in mice with LD50 values greater than 15000.0 mg/kg and 8200.0 mg/kg for different assessments..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	A natural, noncaloric sweetener with a potency 300 times more than that of regular sucrose. Exhibits transepithelial p-aminohippurate transport via organic anion transport system interference.
别名	甜菊苷, 蛇菊苷

化学信息

分子量	804.87
分子式	C₃₈H₆₀O₁₈
CAS No.	57817-89-7
Smiles	C[C@@]12CCC[C@](C)(C1CC[C@@]13CC(=C)[C@](C1)(CCC23)O[C@H]1O[C@H](CO)C(O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)O[C@@H]1O[C@H](CO)C(O)[C@H](O)C1O
密度	1.53 g/cm3 (Predicted)

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 80.5 mg/mL (100.02 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (4.1 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2424 mL	6.2122 mL	12.4244 mL	62.1218 mL
5 mM	0.2485 mL	1.2424 mL	2.4849 mL	12.4244 mL
10 mM	0.1242 mL	0.6212 mL	1.2424 mL	6.2122 mL
20 mM	0.0621 mL	0.3106 mL	0.6212 mL	3.1061 mL
50 mM	0.0248 mL	0.1242 mL	0.2485 mL	1.2424 mL
100 mM	0.0124 mL	0.0621 mL	0.1242 mL	0.6212 mL