Name: IGF2BP1-IN-1
Brand: TargetMol
SKU: T79724
Price: 1599 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 1,599

现货

生物活性

产品描述	IGF2BP1-IN-1 is a highly efficient IGF2BP1 inhibitor with anti-cancer and anti-proliferative activities. It binds to insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and inhibits tumor growth. It can be used for research on lung cancer.
靶点活性	IGF2BP1 protein:2.88 nM (KD), A549 cells:9 nM, HCT116 cells:34 nM
体外活性	IGF2BP1-IN-1与 IGF2BP1 蛋白结合,KD 值 2.88 nM。IGF2BP1-IN-1对癌细胞增殖具有抑制作用，其 IC50 对 A549 细胞为 9 nM，对 HCT116 细胞为 34 nM。[1]

化学信息

分子量	777.87
分子式	C₄₂H₅₂FN₃O₁₀
CAS No.	3029447-08-0
Smiles	C[C@]12[C@]3([C@](C)([C@]4(C(=CC3)C(C)(C)C(=O)[C@@H](OC(CN5C(=O)N(C=N5)C6=CC=C(F)C=C6)=O)C4)[H])C(=O)C[C@]1(C)[C@@]([C@@](C(/C=C/C(OC(C)=O)(C)C)=O)(C)O)([C@H](O)C2)[H])[H]

储存&溶解度

存储

keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 80 mg/mL (102.84 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2856 mL	6.4278 mL	12.8556 mL	64.2781 mL
5 mM	0.2571 mL	1.2856 mL	2.5711 mL	12.8556 mL
10 mM	0.1286 mL	0.6428 mL	1.2856 mL	6.4278 mL
20 mM	0.0643 mL	0.3214 mL	0.6428 mL	3.2139 mL
50 mM	0.0257 mL	0.1286 mL	0.2571 mL	1.2856 mL
100 mM	0.0129 mL	0.0643 mL	0.1286 mL	0.6428 mL