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Spinosyn A

Name: Spinosyn A
Brand: TargetMol
SKU: T21495
Price: 1510 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.85%

货号 T21495Cas号 131929-60-7

别名 多杀霉素 A

Spinosyn A 是聚酮化合物衍生的大环内酯，来自多刺甘蔗多孢菌。Spinosyn A 是有效的杀虫剂。

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Spinosyn A

一键复制产品信息

很棒

纯度: 99.85%

货号 T21495 别名 多杀霉素 ACas号 131929-60-7

Spinosyn A 是聚酮化合物衍生的大环内酯，来自多刺甘蔗多孢菌。Spinosyn A 是有效的杀虫剂。

规格	价格	库存
1 mg	¥ 1,510	现货
2 mg	¥ 2,230	现货
5 mg	¥ 3,570	现货
10 mg	¥ 4,910	现货
25 mg	¥ 7,380	现货
50 mg	¥ 9,800	现货
100 mg	¥ 13,500	现货
200 mg	¥ 18,200	现货
1 mL x 10 mM (in DMSO)	¥ 5,690	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

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产品介绍

Spinosyn A AI Summary

Spinosyn A exhibits a broad range of bioactivities, demonstrating both insecticidal and antiproliferative properties. In terms of its insecticidal activity, Spinosyn A is effective against beet armyworm and tobacco budworm eggs, with minimum emergent larvicide concentrations of 3.0 ppm and 0.4 ppm, respectively, observed after 6 to 7 days. It also inhibits the growth of beet armyworm eggs with a minimum inhibitory concentration (MIC) of 0.02 ppm at 28°C in a lepidopteran diet assay. Additionally, the compound shows significant activity against various pests such as cotton aphid, green peach aphid, sweet potato whitefly, cabbage looper, and two-spotted spider mites, with efficacy indicated by LC50 values. Regarding its antiproliferative action, Spinosyn A is effective against several human cancer cell lines, including MCF7, HCT116, NCI-H460, and U87MG. It displays different levels of potency, with IC50 values of 17900.0 nM for MCF7 cells, 11100.0 nM for HCT116 cells, 67500.0 nM for NCI-H460 cells, and 96500.0 nM for U87MG cells after 48 hours based on the MTT assay. The compound induces apoptosis in NCI-H460 cells, as observed through flow cytometric analysis using Annexin V-FITC/propidium iodide staining, affecting necrotic, late apoptotic, early apoptotic, and viable cells at varying concentrations..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Spinosyn A is a polyketide-derived macrolide produced by Saccharopolyspora spinosa and is an active ingredient in several commercial insecticides.
别名	多杀霉素 A

化学信息

分子量	731.96
分子式	C₄₁H₆₅NO₁₀
CAS No.	131929-60-7
Smiles	[H][C@@]12C[C@H](C[C@@]1([H])[C@]1([H])C=C3C(=O)[C@H](C)[C@H](CCC[C@H](CC)OC(=O)C[C@@]3([H])[C@]1([H])C=C2)O[C@@]1([H])CC[C@@H]([C@@H](C)O1)N(C)C)O[C@]1([H])O[C@@H](C)[C@H](OC)[C@@H](OC)[C@H]1OC
密度	1.31g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 10 mg/mL (13.66 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3662 mL	6.8310 mL	13.6619 mL	68.3097 mL
5 mM	0.2732 mL	1.3662 mL	2.7324 mL	13.6619 mL
10 mM	0.1366 mL	0.6831 mL	1.3662 mL	6.8310 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。